β-1 and β-2 adrenoceptors (AR) play a pivotal role in regulation of the activity of the
sympathetic nervous system and agonists and antagonists at both β AR subtypes are …

Administration of short-term tocolytic agents can prolong pregnancy for women in preterm
labor. Prolonging pregnancy has many benefits because it allows for other proven …

Oxytocin has been used for many years in obstetric practice for the induction and
augmentation of labour, and for the prevention of postpartum haemorrhage (Zeeman et al …

To assess whether pregnancy might influence the functionality and expression of human
myometrial β2-and β3-adrenoceptors (β2-and β3-AR), we performed functional, binding …

Operative vaginal delivery remains a valid option when problems arise in the second stage
of labor. The most common indications are fetal compromise and failure to deliver …

Preterm birth (before 37 completed weeks of gestation) continues to account for the vast
majority of neonatal morbidity and mortality. The incidence of preterm birth can be reduced …

Attenuation of CRH receptor type 1 (CRH-R1) signaling activity might involve desensitization
and uncoupling of CRH-R1 from intracellular effectors. We investigated the desensitization …

The regulation of uterine relaxation is poorly understood but research in myometrial tissue
and other types of smooth muscle has defined a number of receptors, ion channels and …

Although significant advances to patient care have been made in various branches of
obstetrics and gynaecology, the incidence of preterm birth has not changed in the past 40 …

The possible existence of a β3‐adrenoceptor (β3‐AR) in human near‐term myometrium was
investigated by in vitro functional and biochemical studies and analysis of mRNA …