[HTML][HTML] The involvement of microRNAs in Bone Remodeling Signaling pathways and their role in the development of osteoporosis
RF Jiménez-Ortega, AI Ortega-Meléndez, N Patiño… - Biology, 2024 - mdpi.com
Simple Summary Osteoporosis is a disease that is characterized by bone mass loss and
microarchitecture deterioration, due to alterations in the bone remodeling mechanism, which …
microarchitecture deterioration, due to alterations in the bone remodeling mechanism, which …
Epigenetic regulation of pulmonary inflammation
Pulmonary disease such as chronic obstructive pulmonary disease (COPD), asthma,
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …
pulmonary fibrosis and pulmonary hypertension are the leading cause of deaths. More …
α-lipoic acid modulates prostate cancer cell growth and bone cell differentiation
Prostate cancer (PCa) progression leads to bone modulation in approximately 70% of
affected men. A nutraceutical, namely, α-lipoic acid (α-LA), is known for its potent anti-cancer …
affected men. A nutraceutical, namely, α-lipoic acid (α-LA), is known for its potent anti-cancer …
Dysregulation of histone modifications in bone marrow mesenchymal stem cells during skeletal ageing: roles and therapeutic prospects
Y Li, M Hu, J **e, S Li, L Dai - Stem Cell Research & Therapy, 2023 - Springer
Age-associated bone diseases such as osteoporosis (OP) are common in the elderly due to
skeletal ageing. The process of skeletal ageing can be accelerated by reduced proliferation …
skeletal ageing. The process of skeletal ageing can be accelerated by reduced proliferation …
Overview on postmenopausal osteoporosis and periodontitis: The therapeutic potential of phytoestrogens against alveolar bone loss
Osteoporosis and periodontitis are two major chronic diseases of postmenopausal women.
The association between these two diseases are evident through systemic bone loss and …
The association between these two diseases are evident through systemic bone loss and …
Krüppel‐like factors family in health and disease
T **ang, C Yang, Z Deng, D Sun, F Luo, Y Chen - MedComm, 2024 - Wiley Online Library
Krüppel‐like factors (KLFs) are a family of basic transcription factors with three conserved
Cys2/His2 zinc finger domains located in their C‐terminal regions. It is acknowledged that …
Cys2/His2 zinc finger domains located in their C‐terminal regions. It is acknowledged that …
Effect of storage time and temperature on the bioactivity of a chitosan-derived epigenetic modulation scaffold
The appropriate storage protocol is one of the main limitations of translating tissue
engineering technology to commercialized clinical applications. Recently, the development …
engineering technology to commercialized clinical applications. Recently, the development …
Hypoxia-cleavable and specific targeted nanomedicine delivers epigenetic drugs for enhanced treatment of breast cancer and bone metastasis
Z Li, P Liu, W Chen, X Liu, F Tong, J Sun… - Journal of …, 2023 - Springer
Breast cancer bone metastasis has become a common cancer type that still lacks an
effective treatment method. Although epigenetic drugs have demonstrated promise in cancer …
effective treatment method. Although epigenetic drugs have demonstrated promise in cancer …
Hydroxychloroquine interaction with phosphoinositide 3-kinase modulates prostate cancer growth in bone microenvironment: In vitro and molecular dynamics based …
Patients with advanced prostate cancer (PCa) are more likely to develop bone metastases.
Tumor cells thrive in the bone microenvironment, interacting with osteoblasts and …
Tumor cells thrive in the bone microenvironment, interacting with osteoblasts and …
Cryoprotective isoliquiritigenin-zein phosphatidylcholine nanoparticles inhibits breast cancer-bone metastasis by targeting JAK-STAT signaling pathways
K Ganesan, C Xu, C **e, Y Sui, C Zheng, F Gao… - Chemico-Biological …, 2024 - Elsevier
Breast cancer (BC) is the most common cancer in women and is known for its tendency to
spread to the bones, causing significant health issues and mortality. In this study, we aimed …
spread to the bones, causing significant health issues and mortality. In this study, we aimed …