Ancient DNA analysis

L Orlando, R Allaby, P Skoglund… - Nature reviews …, 2021 - nature.com
Although the first ancient DNA molecules were extracted more than three decades ago, the
first ancient nuclear genomes could only be characterized after high-throughput sequencing …

The influence of evolutionary history on human health and disease

ML Benton, A Abraham, AL LaBella, P Abbot… - Nature Reviews …, 2021 - nature.com
Nearly all genetic variants that influence disease risk have human-specific origins; however,
the systems they influence have ancient roots that often trace back to evolutionary events …

The Allen Ancient DNA Resource (AADR) a curated compendium of ancient human genomes

S Mallick, A Micco, M Mah, H Ringbauer, I Lazaridis… - Scientific Data, 2024 - nature.com
More than two hundred papers have reported genome-wide data from ancient humans.
While the raw data for the vast majority are fully publicly available testifying to the …

Palaeogenomics of upper palaeolithic to neolithic European hunter-gatherers

C Posth, H Yu, A Ghalichi, H Rougier, I Crevecoeur… - Nature, 2023 - nature.com
Modern humans have populated Europe for more than 45,000 years,. Our knowledge of the
genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to …

[HTML][HTML] Population genomics of post-glacial western Eurasia

ME Allentoft, M Sikora, A Refoyo-Martínez… - Nature, 2024 - nature.com
Western Eurasia witnessed several large-scale human migrations during the Holocene,,,–.
Here, to investigate the cross-continental effects of these migrations, we shotgun-sequenced …

Grey wolf genomic history reveals a dual ancestry of dogs

A Bergström, DWG Stanton, UH Taron, L Frantz… - Nature, 2022 - nature.com
The grey wolf (Canis lupus) was the first species to give rise to a domestic population, and
they remained widespread throughout the last Ice Age when many other large mammal …

The genetic history of the Southern Arc: A bridge between West Asia and Europe

I Lazaridis, S Alpaslan-Roodenberg, A Acar, A Açıkkol… - Science, 2022 - science.org
By sequencing 727 ancient individuals from the Southern Arc (Anatolia and its neighbors in
Southeastern Europe and West Asia) over 10,000 years, we contextualize its Chalcolithic …

Large-scale migration into Britain during the Middle to Late Bronze Age

N Patterson, M Isakov, T Booth, L Büster, CE Fischer… - Nature, 2022 - nature.com
Present-day people from England and Wales have more ancestry derived from early
European farmers (EEF) than did people of the Early Bronze Age. To understand this, here …

The source of the Black Death in fourteenth-century central Eurasia

MA Spyrou, L Musralina, GA Gnecchi Ruscone… - Nature, 2022 - nature.com
The origin of the medieval Black Death pandemic (ad 1346–1353) has been a topic of
continuous investigation because of the pandemic's extensive demographic impact and long …

Dairying, diseases and the evolution of lactase persistence in Europe

RP Evershed, G Davey Smith, M Roffet-Salque… - Nature, 2022 - nature.com
Abstract In European and many African, Middle Eastern and southern Asian populations,
lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over …