Cellular senescence and cancer: Focusing on traditional Chinese medicine and natural products

Y Liu, S Yang, K Wang, J Lu, X Bao, R Wang… - Cell …, 2020 - Wiley Online Library
Cancer is the principal cause of death and a dominant public health problem which
seriously threatening human life. Among various ways to treat cancer, traditional Chinese …

Anticancer effects and mechanisms of berberine from medicinal herbs: An update review

RG **ong, SY Huang, SX Wu, DD Zhou, ZJ Yang… - Molecules, 2022 - mdpi.com
Cancer has been a serious public health problem. Berberine is a famous natural compound
from medicinal herbs and shows many bioactivities, such as antioxidant, anti-inflammatory …

Berberine in combination with cisplatin induces necroptosis and apoptosis in ovarian cancer cells

L Liu, J Fan, G Ai, J Liu, N Luo, C Li, Z Cheng - Biological research, 2019 - Springer
Background Berberine (BBR), a compound extracted from a variety of medicinal herbs, has
been shown multiple pharmacological effects against cancer cells of different origins …

[HTML][HTML] Alkaloids from traditional Chinese medicine against hepatocellular carcinoma

C Liu, S Yang, K Wang, X Bao, Y Liu, S Zhou… - Biomedicine & …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) has become one of the major diseases that are threatening
human health in the 21st century. Currently there are many approaches to treat liver cancer …

Apoptosis induction, a sharp edge of berberine to exert anti-cancer effects, focus on breast, lung, and liver cancer

Y Zhu, N **e, Y Chai, Y Nie, K Liu, Y Liu… - Frontiers in …, 2022 - frontiersin.org
Cancer is the leading cause of death and one of the greatest barriers to increased life
expectancy worldwide. Currently, chemotherapy with synthetic drugs remains one of the …

α-Humulene inhibits hepatocellular carcinoma cell proliferation and induces apoptosis through the inhibition of Akt signaling

H Chen, J Yuan, J Hao, Y Wen, Y Lv, L Chen… - Food and Chemical …, 2019 - Elsevier
Hepatocellular carcinoma (HCC) is a prevalent malignancy and a leading cause of cancer-
related mortality. α-Humulene (HML) is a natural 11-membered monocyclic terpene with …

Recent advances in berberine inspired anticancer approaches: from drug combination to novel formulation technology and derivatization

S Habtemariam - Molecules, 2020 - mdpi.com
Berberine is multifunctional natural product with potential to treat diverse pathological
conditions. Its broad-spectrum anticancer effect through direct effect on cancer cell growth …

Current understanding and future prospects on Berberine for anticancer therapy

A Goel - Chemical Biology & Drug Design, 2023 - Wiley Online Library
Berberine (BBR) is a potential plant metabolite and has remarkable anticancer properties.
Many kinds of research are being focused on the cytotoxic activity of berberine in in vitro and …

CDKN1A/p21 in Breast Cancer: Part of the Problem, or Part of the Solution?

E Manousakis, CM Miralles, MG Esquerda… - International Journal of …, 2023 - mdpi.com
Cyclin-dependent kinase inhibitor 1A (Cip1/Waf1/CDKN1A/p21) is a well-established
protein, primarily recognised for its pivotal role in the cell cycle, where it induces cell cycle …

Identifying cancer-related molecular targets of Nandina domestica Thunb. by network pharmacology-based analysis in combination with chemical profiling and …

KF Taha, M Khalil, MS Abubakr, E Shawky - Journal of ethnopharmacology, 2020 - Elsevier
Ethnopharmacological relevance The fruits of Nandina domestica Thunb. have served as
folk medicines in Chinese and Japanese tradition for treatment of several tumors including …