Is the antidepressant activity of selective serotonin reuptake inhibitors mediated by nicotinic acetylcholine receptors?

HR Arias, KM Targowska-Duda, J García-Colunga… - Molecules, 2021 - mdpi.com
It is generally assumed that selective serotonin reuptake inhibitors (SSRIs) induce
antidepressant activity by inhibiting serotonin (5-HT) reuptake transporters, thus elevating …

Memantine inhibits α3β2-nAChRs-mediated nitrergic neurogenic vasodilation in porcine basilar arteries

RHC Lee, TY Tseng, CYC Wu, PY Chen, MF Chen… - PloS one, 2012 - journals.plos.org
Memantine, an NMDA receptor antagonist used for treatment of Alzheimer's disease (AD), is
known to block the nicotinic acetylcholine receptors (nAChRs) in the central nervous system …

Betulinic acid-induced expression of nicotinamide adenine dinucleotide phosphate-diaphorase in the immune organs of mice: A possible role of nitric oxide in …

KL Pang, K Vijayaraghavan… - Molecular …, 2018 - spandidos-publications.com
The aim of the present study was to investigate the effects of betulinic acid (BetA) on the
expression and distribution pattern of nicotinamide adenine dinucleotide phosphate …

Differential blockade by huperzine A and donepezil of sympathetic nicotinic acetylcholine receptor-mediated nitrergic neurogenic dilations in porcine basilar arteries

CC Shih, PY Chen, MF Chen, TJF Lee - European Journal of …, 2020 - Elsevier
Nicotinic acetylcholine receptor activation on the perivascular sympathetic nerves via axo-
axonal interaction mechanism causes norepinephrine release, which triggers the …

L‐type calcium channels in sympathetic α3β2‐nAChR‐mediated cerebral nitrergic neurogenic vasodilation

CYC Wu, RHC Lee, PY Chen, APY Tsai… - Acta …, 2014 - Wiley Online Library
Aim Nicotine stimulation of α3β2‐nicotinic acetylcholine receptors (α3β2‐n AC hRs) located
on sympathetic nerves innervating basilar arteries causes calcium‐dependent …

Natural Product Goniothalamin Induced NADPH-Diaphorase Expression in the Liver: A Possible Role of Nitric Oxide in Hepatoprotection

HM Yap, AF Albalawi, NH Alhussain, AH Alharbi… - Indian Journal of …, 2024 - ijper.org
Materials and Methods Mice were randomly assigned to four main groups (n= 72):
Experimental group (GTN), positive control group (Betulinic acid; BetA), vehicle control …

Inductively coupled plasma-optical emission spectrometric determination of some elements from Anchusa azurea mill. collected in Iraqi Kurdistan Region

PS Osw, FHS Hussain - EURASIAN JOURNAL OF SCIENCE AND …, 2020 - eajse.tiu.edu.iq
The Anchusa azurea Mill.(Boraginaceae) is naturally grown in the Kurdistan Region of Iraq
and one of those plants that are used by many Kurdish people for cooking especially in the …

[PDF][PDF] Functional and structural interactions between selective serotonin reuptake inhibitors and nicotinic acetylcholine receptors

J García-Colunga, KM Targowska-Duda… - Neurotransmitter, 2016 - academia.edu
Neuronal nicotinic acetylcholine receptors (nAChRs) are involved in the regulation of mood
and their related disorders such as anxiety and major depressive disorder. For instance …

Inhibition by ketamine and amphetamine analogs of the neurogenic nitrergic vasodilations in porcine basilar arteries

MF Chen, SY Lai, PC Kung, YC Lin, HI Yang… - Toxicology and Applied …, 2016 - Elsevier
The abuse of ketamine and amphetamine analogs is associated with incidence of
hypertension and strokes involving activation of sympathetic activities. Large cerebral …

[PDF][PDF] Histological interfaces of liver, kidney and cerebrum in male rats exposed to fluoxetine

SH Hamad, DH Hassan, KH Rasul… - ZANCO J Pure Appl …, 2016 - researchgate.net
Fluoxetine is an antidepressant of selective serotonin reuptake inhibitor drug. It is used in
treatment of depression, panic and anxiety. Also, it may decrease the risk of suicide in those …