Sperm selection in the female reproductive tract (FRT) is sophisticated. Only about 1,000
sperm out of millions in an ejaculate reach the fallopian tube and thus have a chance of …

STUDY QUESTION What is the role of carbohydrates in the binding of human sperm to the
zona pellucida (ZP) and what are potential implications for pathogenesis? SUMMARY …

Fertilization depends on successful binding of the spermatozoa to the zona pellucida of the
oocyte. Glycodelin-A inhibits spermatozoa-zona pellucida binding. Previous data showed …

The human egg may only be fertilized by one spermatozoon to prevent polyploidy. In most
mammals, the primary block to polyspermy occurs at the zona pellucida (ZP). Little is known …

Mammalian fertilization usually requires three sequential cell–cell interactions:(i) initial
binding of sperm to the specialized extracellular matrix coating the egg known as the zona …

Human oocytes from the same as well as from different patients have an extremely
heterogeneous morphology of the zona pellucida surface as shown by scanning electron …

Diabetes mellitus (DM) represents one of the greatest concerns to global health and it is
associated with diverse clinical complications, including reproductive dysfunction. Given the …

The study aimed to establish zona pellucida induced acrosome reaction response (ZIAR)
among 35 couples with normal and G-pattern sperm morphology and repeated poor …

Previous studies showed that zona binding inhibitory factor-1 (ZIF-1) was the glycoprotein
mainly responsible for the spermatozoa zona binding inhibitory activity of human follicular …

The binding of spermatozoa to the zona pellucida is an initial and crucial step in fertilization.
Studies of sperm–zona pellucida interactions have been used both for understanding details …