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[HTML][HTML] Implication of trimethylamine N-oxide (TMAO) in disease: potential biomarker or new therapeutic target
Trimethylamine N-oxide (TMAO) is a molecule generated from choline, betaine, and
carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several …
carnitine via gut microbial metabolism. The plasma level of TMAO is determined by several …
Gut microbiota-dependent marker TMAO in promoting cardiovascular disease: inflammation mechanism, clinical prognostic, and potential as a therapeutic target
S Yang, X Li, F Yang, R Zhao, X Pan, J Liang… - Frontiers in …, 2019 - frontiersin.org
Cardiovascular disease (CVD) is the leading cause of death worldwide, especially in
developed countries, and atherosclerosis (AS) is the common pathological basis of many …
developed countries, and atherosclerosis (AS) is the common pathological basis of many …
Trimethylamine-N-oxide promotes age-related vascular oxidative stress and endothelial dysfunction in mice and healthy humans
Age-related vascular endothelial dysfunction is a major antecedent to cardiovascular
diseases. We investigated whether increased circulating levels of the gut microbiome …
diseases. We investigated whether increased circulating levels of the gut microbiome …
Total volatile basic nitrogen and trimethylamine in muscle foods: Potential formation pathways and effects on human health
The use of total volatile basic nitrogen (TVB‐N) as a quality parameter for fish is rapidly
growing to include other types of meat. Investigations of meat quality have recently focused …
growing to include other types of meat. Investigations of meat quality have recently focused …
Gut microbiota-dependent metabolite trimethylamine N-oxide contributes to cardiac dysfunction in western diet-induced obese mice
K Chen, X Zheng, M Feng, D Li, H Zhang - Frontiers in physiology, 2017 - frontiersin.org
Excessive consumption of diets high in sugars and saturated fat, frequently known as
western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows …
western diet (WD), may lead to obesity and metabolic syndrome. Recent evidence shows …
Relationship of serum trimethylamine N-oxide (TMAO) levels with early atherosclerosis in humans
E Randrianarisoa, A Lehn-Stefan, X Wang, M Hoene… - Scientific reports, 2016 - nature.com
Abstract Circulating trimethylamine N-Oxide (TMAO) levels predict cardiovascular disease
(CVD), possibly by impacting on cholesterol metabolism and oxidative stress. Because …
(CVD), possibly by impacting on cholesterol metabolism and oxidative stress. Because …
The gut microbiome–derived metabolite trimethylamine N-oxide modulates neuroinflammation and cognitive function with aging
Aging is associated with declines in cognitive performance, which are mediated in part by
neuroinflammation, characterized by astrocyte activation and higher levels of pro …
neuroinflammation, characterized by astrocyte activation and higher levels of pro …
The role of a gut microbial-derived metabolite, trimethylamine N-oxide (TMAO), in neurological disorders
Trimethylamine lyases are expressed in a wide range of intestinal microbiota which
metabolize dietary nutrients like choline, betaine, and L-carnitine to form trimethylamine …
metabolize dietary nutrients like choline, betaine, and L-carnitine to form trimethylamine …
Trimethylamine N-oxide (TMAO), diet and cardiovascular disease
Abstract Purpose of Review The association between plasma Trimethylamine N-Oxide
(TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While …
(TMAO), diet and risk for cardiovascular disease (CVD) is still not fully understood. While …
[HTML][HTML] Gut Microbiota-Dependent Trimethylamine-N-oxide and Serum Biomarkers in Patients with T2DM and Advanced CKD
Trimethylamine-N-oxide (TMAO) is a product of dietary, gut microbiome, and tissues
metabolism. Elevated blood TMAO levels are associated with heart attack, stroke and …
metabolism. Elevated blood TMAO levels are associated with heart attack, stroke and …