Using machine learning approaches for multi-omics data analysis: A review

PS Reel, S Reel, E Pearson, E Trucco… - Biotechnology advances, 2021‏ - Elsevier
With the development of modern high-throughput omic measurement platforms, it has
become essential for biomedical studies to undertake an integrative (combined) approach to …

A roadmap for multi-omics data integration using deep learning

M Kang, E Ko, TB Mersha - Briefings in Bioinformatics, 2022‏ - academic.oup.com
High-throughput next-generation sequencing now makes it possible to generate a vast
amount of multi-omics data for various applications. These data have revolutionized …

A benchmark study of deep learning-based multi-omics data fusion methods for cancer

D Leng, L Zheng, Y Wen, Y Zhang, L Wu, J Wang… - Genome biology, 2022‏ - Springer
Background A fused method using a combination of multi-omics data enables a
comprehensive study of complex biological processes and highlights the interrelationship of …

Dealing with dimensionality: the application of machine learning to multi-omics data

D Feldner-Busztin, P Firbas Nisantzis… - …, 2023‏ - academic.oup.com
Motivation Machine learning (ML) methods are motivated by the need to automate
information extraction from large datasets in order to support human users in data-driven …

Survey on multi-omics, and multi-omics data analysis, integration and application

MH Shahrajabian, W Sun - Current Pharmaceutical Analysis, 2023‏ - benthamdirect.com
Multi-omics approaches have developed as a profitable technique for plant systems, a
popular method in medical and biological sciences underlining the necessity to outline new …

Integrated multi-omics analysis of ovarian cancer using variational autoencoders

MT Hira, MA Razzaque, C Angione, J Scrivens… - Scientific reports, 2021‏ - nature.com
Cancer is a complex disease that deregulates cellular functions at various molecular levels
(eg, DNA, RNA, and proteins). Integrated multi-omics analysis of data from these levels is …

Advances in bulk and single-cell multi-omics approaches for systems biology and precision medicine

Y Li, L Ma, D Wu, G Chen - Briefings in Bioinformatics, 2021‏ - academic.oup.com
Multi-omics allows the systematic understanding of the information flow across different
omics layers, while single omics can mainly reflect one aspect of the biological system. The …

[HTML][HTML] Multi-omics analysis based on 3D-bioprinted models innovates therapeutic target discovery of osteosarcoma

Y Lin, Y Yang, K Yuan, S Yang, S Zhang, H Li, T Tang - Bioactive materials, 2022‏ - Elsevier
Current in vitro models for osteosarcoma investigation and drug screening, including two-
dimensional (2D) cell culture and tumour spheroids (ie cancer stem-like cells), lack …

Application of deep learning in cancer epigenetics through DNA methylation analysis

M Yassi, A Chatterjee, M Parry - Briefings in bioinformatics, 2023‏ - academic.oup.com
DNA methylation is a fundamental epigenetic modification involved in various biological
processes and diseases. Analysis of DNA methylation data at a genome-wide and high …

Deep reinforced neural network model for cyto-spectroscopic analysis of epigenetic markers for automated oral cancer risk prediction

A Ghosh, D Chaudhuri, S Adhikary, K Chatterjee… - Chemometrics and …, 2022‏ - Elsevier
Understanding epigenetic changes can provide vital information for early stage oral cancer
diagnosis. Vibrational spectroscopy methods like Raman spectroscopy (RS) and Fourier …