CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
S Jain, C Bakolitsa, SE Brenner, P Radivojac… - Genome …, 2024 - lirias.kuleuven.be
Abstract Background: The Critical Assessment of Genome Interpretation (CAGI) aims to
advance the state-of-the-art for computational prediction of genetic variant impact …
advance the state-of-the-art for computational prediction of genetic variant impact …
CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods
Genome biology, 2024 - Springer
Abstract Background The Critical Assessment of Genome Interpretation (CAGI) aims to
advance the state-of-the-art for computational prediction of genetic variant impact …
advance the state-of-the-art for computational prediction of genetic variant impact …
[HTML][HTML] Deep learning and citizen science enable automated plant trait predictions from photographs
Abstract Plant functional traits ('traits') are essential for assessing biodiversity and ecosystem
processes, but cumbersome to measure. To facilitate trait measurements, we test if traits can …
processes, but cumbersome to measure. To facilitate trait measurements, we test if traits can …
Reports from the fifth edition of CAGI: The Critical Assessment of Genome Interpretation
Abstract Interpretation of genomic variation plays an essential role in the analysis of cancer
and monogenic disease, and increasingly also in complex trait disease, with applications …
and monogenic disease, and increasingly also in complex trait disease, with applications …
Weakly-supervised transfer learning with application in precision medicine
Precision medicine aims to provide diagnosis and treatment accounting for individual
differences. To develop machine learning models in support of precision medicine …
differences. To develop machine learning models in support of precision medicine …
Critical assessment of genome interpretation consortium. CAGI, the critical assessment of genome interpretation, establishes progress and pprospects for …
Background: The Critical Assessment of Genome Interpretation (CAGI) aims to advance the
state-of-the-art for computational prediction of genetic variant impact, particularly where …
state-of-the-art for computational prediction of genetic variant impact, particularly where …
Assessment of blind predictions of the clinical significance of BRCA1 and BRCA2 variants
Testing for variation in BRCA1 and BRCA2 (commonly referred to as BRCA1/2), has
emerged as a standard clinical practice and is hel** countless women better understand …
emerged as a standard clinical practice and is hel** countless women better understand …
Assessing the performance of in silico methods for predicting the pathogenicity of variants in the gene CHEK2, among Hispanic females with breast cancer
The availability of disease‐specific genomic data is critical for develo** new
computational methods that predict the pathogenicity of human variants and advance the …
computational methods that predict the pathogenicity of human variants and advance the …
Bayesian modeling and uncertainty quantification for learning to optimize: What, why, and how
Optimizing an objective function with uncertainty awareness is well-known to improve the
accuracy and confidence of optimization solutions. Meanwhile, another relevant but very …
accuracy and confidence of optimization solutions. Meanwhile, another relevant but very …
[ZITATION][C] Circumventing Drug Resistance by Molecular Design: Exact Combinatorial Optimization and Deep Generative Models
M Karimi - 2020