Future therapies for chronic hepatitis C

NM Dabbouseh, DM Jensen - Nature Reviews Gastroenterology & …, 2013 - nature.com
Therapy for hepatitis C has been fairly stagnant for the past decade, but the past few years
have seen major progress and evolution, beginning with the approval of two HCV protease …

[HTML][HTML] HCV infection selectively impairs type I but not type III IFN signaling

PK Chandra, L Bao, K Song, FM Aboulnasr… - The American journal of …, 2014 - Elsevier
A stable and persistent Hepatitis C virus (HCV) replication cell culture model was developed
to examine clearance of viral replication during long-term treatment using interferon-α (IFN …

Adaptive immune responses in primary cutaneous sarcoidosis

M Bordignon, P Rottoli, C Agostini… - Journal of Immunology …, 2011 - Wiley Online Library
Sarcoidosis is a multisystemic inflammatory disorder with cutaneous lesions present in
about one‐quarter of the patients. Cutaneous lesions have been classified as specific and …

Younger hepatocellular carcinoma patients have better prognosis after percutaneous radiofrequency ablation therapy

WY Kao, YY Chiou, HH Hung, CW Su… - Journal of clinical …, 2012 - journals.lww.com
Background: Whether age plays an important role in the outcomes of HCC after RFA
remains controversial. Study: Two hundred fifty-eight consecutive treatment naive HCC …

Successful anti‐viral treatment improves survival of patients with advanced liver disease due to chronic hepatitis C

K Rutter, AF Stättermayer, S Beinhardt… - Alimentary …, 2015 - Wiley Online Library
Background Long‐term outcome of chronic hepatitis C patients with successful viral
eradication seems to be promising. Aim To evaluate mortality, incidence of hepatocellular …

[HTML][HTML] Long-term outcome of chronic hepatitis C patients with sustained virological response to peginterferon plus ribavirin

M Trapero-Marugán, J Mendoza… - World journal of …, 2011 - ncbi.nlm.nih.gov
AIM: To assess the clinical, biochemical and virological long-term outcome in chronic
hepatitis C (CHC) patients with a sustained virological response (SVR) after peginterferon …

Impact of ledipasvir/sofosbuvir on the work productivity of genotype 1 chronic hepatitis C patients in Asia

ZM Younossi, HLY Chan, YY Dan… - Journal of Viral …, 2018 - Wiley Online Library
Chronic, untreated hepatitis C virus (HCV) infection is associated with a poor clinical
prognosis and a detrimental impact on patients' lives, including on work productivity. To …

Utilization and efficacy of elbasvir/grazoprevir for treating hepatitis C virus infection after liver transplantation

S Miuma, H Miyaaki, A Soyama, M Hidaka… - Hepatology …, 2018 - Wiley Online Library
Aim Recently, elbasvir/grazoprevir combination therapy (EBR/GZR) was reported to have
excellent antiviral effects for chronic genotype 1 hepatitis C virus (HCV) infection. However, it …

[HTML][HTML] Interferón alfa-2b y ribavirina como tratamiento combinado para la hepatitis C crónica en Cuba: Programa Nacional

H Nodarse-Cuní, E Arús-Soler… - Biotecnología …, 2012 - scielo.sld.cu
El porcentaje de recaída tras el tratamiento de la hepatitis C crónica con interferón alfa (IFN-
a) es elevado y la respuesta sostenida oscila entre el 10 y el 20%. El efecto antiviral …

The potential use of Toll-like receptor agonists to restore the dysfunctional immunity induced by hepatitis C virus

ML Salem, ELD Maha, AR Abou El-Azm - Cellular immunology, 2010 - Elsevier
Hepatitis C virus (HCV) infection is a major public health concern with approximately 3% of
the world's population is infected, posing social, economical and health burden. Less than …