DAB2+ macrophages support FAP+ fibroblasts in sha** tumor barrier and inducing poor clinical outcomes in liver cancer

F Long, W Zhong, F Zhao, Y Xu, X Hu, G Jia… - …, 2024 - pmc.ncbi.nlm.nih.gov
Background: Cancer-associated fibroblasts (CAFs) are the key components of the immune
barrier in liver cancer. Therefore, gaining a deeper understanding of the heterogeneity and …

Single-cell multiomics: a new frontier in drug research and development

J Ma, C Dong, A He, H **ong - Frontiers in Drug Discovery, 2024 - frontiersin.org
Single-cell multiomics (sc-multiomics) is a burgeoning field that simultaneously integrates
multiple layers of molecular information, enabling the characterization of dynamic cell states …

Harnessing Agent-Based Modeling in CellAgentChat to Unravel Cell-Cell Interactions from Single-Cell Data

V Raghavan, Y Li, J Ding - bioRxiv, 2023 - biorxiv.org
Deciphering cell-cell interactions is crucial yet challenging, given the inherent intricacy and
heterogeneity of cellular dynamics within biological systems. Existing methodologies …