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Advancements and challenges in brain cancer therapeutics
F Bai, Y Deng, L Li, M Lv, J Razzokov, Q Xu, Z Xu… - …, 2024 - Wiley Online Library
Treating brain tumors requires a nuanced understanding of the brain, a vital and delicate
organ. Location, size, tumor type, and surrounding tissue health are crucial in develo** …
organ. Location, size, tumor type, and surrounding tissue health are crucial in develo** …
[PDF][PDF] Modern radiation therapy for the management of brain metastases from non-small cell lung cancer: current approaches and future directions
C Mantovani, A Gastino, M Cerrato, S Badellino… - Frontiers in …, 2021 - frontiersin.org
Brain metastases (BMs) represent the most frequent event during the course of Non-Small
Cell Lung Cancer (NSCLC) disease. Recent advancements in the diagnostic and …
Cell Lung Cancer (NSCLC) disease. Recent advancements in the diagnostic and …
Whole-brain irradiation with hippocampal sparing and dose escalation on metastases: neurocognitive testing and biological imaging (HIPPORAD)–a phase II …
AL Grosu, L Frings, I Bentsalo, O Oehlke, F Brenner… - BMC cancer, 2020 - Springer
Background Whole brain radiation therapy (WBRT) is the standard therapy for multiple brain
metastases. However, WBRT has a poor local tumor control and is associated with a decline …
metastases. However, WBRT has a poor local tumor control and is associated with a decline …
Novel mechanisms and future opportunities for the management of radiation necrosis in patients treated for brain metastases in the era of immunotherapy
Simple Summary As the incidence and survival of patients with brain metastases improve,
the burden of treatment-related neurotoxicities will increase for patients and healthcare …
the burden of treatment-related neurotoxicities will increase for patients and healthcare …
PRO: Do we still need whole-brain irradiation for brain metastases?
I Popp, NE Hartong, C Nieder, AL Grosu - Cancers, 2023 - mdpi.com
Simple Summary Whole-brain radiation therapy (WBRT) has been a mainstay in the
treatment of multiple cerebral metastases for many decades. However, evidence of its …
treatment of multiple cerebral metastases for many decades. However, evidence of its …
Hippocampus-avoidance whole-brain radiation therapy is efficient in the long-term preservation of hippocampal volume
Background and Purpose With improved life expectancy, preventing neurocognitive decline
after cerebral radiotherapy is gaining more importance. Hippocampal damage has been …
after cerebral radiotherapy is gaining more importance. Hippocampal damage has been …
Efficacy of whole-brain radiotherapy plus simultaneous integrated boost (SIB-WBRT) for lung cancer brain metastases
Objective: To investigate the outcomes of SIB-WBRT in patients with brain metastases and
analyze the impact of some factors on prognosis. Materials and Methods: This single-arm …
analyze the impact of some factors on prognosis. Materials and Methods: This single-arm …
Advances in radiotherapy for brain metastases
Brain metastases are the most common central nervous system (CNS) tumor in the adult
population and are projected to increase in incidence as survival outcomes improve for …
population and are projected to increase in incidence as survival outcomes improve for …
Hippocampal avoidance in whole brain radiotherapy and prophylactic cranial irradiation: a systematic review and meta-analysis
Purpose We systematically reviewed the current landscape of hippocampal-avoidance
radiotherapy, focusing specifically on rates of hippocampal tumor recurrence and changes …
radiotherapy, focusing specifically on rates of hippocampal tumor recurrence and changes …
Automated contouring and planning pipeline for hippocampal-avoidant whole-brain radiotherapy
Background Whole-brain radiotherapy (WBRT) remains an important treatment for over
200,000 cancer patients in the United States annually. Hippocampal-avoidant WBRT (HA …
200,000 cancer patients in the United States annually. Hippocampal-avoidant WBRT (HA …