Drugs that interfere with cannabinoid CB1 receptor transmission suppress a number of food-
related behaviors, and these compounds are currently being assessed for their potential …

Detoxification from drug abuse is strongly threatened by the occurrence of renewed
episodes of drug intake. In human addicts, relapse to drug seeking may take place even …

BACKGROUND AND PURPOSE Cannabinoid CB1 receptor antagonists reduce food intake
and body weight, but clinical use in humans is limited by effects on the CNS. We have …

Drugs that interfere with cannabinoid CB1 transmission suppress various food-motivated
behaviors, and it has been suggested that such drugs could be useful as appetite …

Rationale Cannabinoid CB1 antagonists/inverse agonists suppress food-motivated
behaviors and are being evaluated as potential appetite suppressants. It has been …

The identification of the CB2 cannabinoid receptor has provided a novel target for the
development of therapeutically useful cannabinergic molecules. We have synthesized …

Cannabinoid (CB) 1 receptor inverse agonists inhibit food intake in animals and humans but
also potentiate emesis. It is not clear whether these effects result from inverse agonist …

Cannabinoid CB1 inverse agonists suppress food-motivated behaviors, but may also induce
psychiatric effects such as depression and anxiety. To evaluate behaviors potentially related …

My involvement with the field of cannabinoids spans close to 3 decades and covers a major
part of my scientific career. It also reflects the robust progress in this initially largely …

Drugs that interfere with cannabinoid CB1 transmission suppress food-motivated behaviors,
and may be useful clinically as appetite suppressants. However, there may also be …