Objective Restenosis is a significant complication of revascularization treatments in coronary
and peripheral arteries, sometimes necessitating repeated intervention. Establishing when …

The success of drug-eluting stents (DES) is limited by restenosis and, to a lesser extent, late
stent thrombosis. Mechanical stimuli have been implicated in these outcomes, with indices …

Background and objectives Bioresorbable braided stents, typically made of bioresorbable
polymers such as poly-l-lactide (PLLA), have great potential in the treatment of critical limb …

Self-expandable transcatheter aortic valves (TAVs) elastically resume their initial shape
when implanted without the need for balloon inflation by virtue of the nickel–titanium (NiTi) …

Abstract Development of in silico models that capture progression of diseases in soft
biological tissues are intrinsic in the validation of the hypothesized cellular and molecular …

Background and objective In-stent restenosis (ISR) following percutaneous coronary
intervention with drug-eluting stent (DES) implantation remains an unresolved issue, with …

Multiscale agent-based modeling frameworks have recently emerged as promising
mechanobiological models to capture the interplay between biomechanical forces, cellular …

Since the introduction of percutaneous coronary intervention (PCI) for the treatment of
obstructive coronary artery disease (CAD), patient outcomes have progressively improved …

In-stent restenosis in superficial femoral arteries (SFAs) is a complex, multi-factorial and
multiscale vascular adaptation process whose thorough understanding is still lacking …

The progression of cardiovascular disease is intricately influenced by a complex interplay
between physiological pathways, biochemical processes, and physical mechanisms. This …