Biocatalysis has revolutionized chemical synthesis, providing sustainable methods for
preparing various organic molecules. In enzyme-mediated organic synthesis, most reactions …

Conspectus Harnessing biocatalysts for novel abiological transformations is a longstanding
goal of synthetic chemistry. Combining the merits of biocatalysis and photocatalysis allows …

Glucose oxidase (GOx) is an important oxidoreductase enzyme with many important roles in
biological processes. It is considered an “ideal enzyme” and is often called an oxidase …

Controlling the enantioselectivity of hydrogen atom transfer (HAT) reactions has been a long-
standing synthetic challenge. While recent advances on photoenzymatic catalysis have …

State-of-the-art non-natural photoenzymatic catalysis typically relies on either ultraviolet light
activation or the formation of electron donor–acceptor complexes. Inspired by nature, herein …

Endogenous photosensitizers play a critical role in both beneficial and harmful light-induced
transformations in biological systems. Understanding their mode of action is essential for …

With the advent of X-ray free-electron lasers (XFELs), new, high-throughput serial
crystallography techniques for macromolecular structure determination have emerged …

Despite their intriguing photophysical and photochemical activities, naturally occurring
photoenzymes have not yet been repurposed for new-to-nature activities. Here we …

Enzymes play an increasingly important role in improving the benignity and efficiency of
chemical production, yet the diversity of their applications lags heavily behind chemical …

Efficient chemical transformation in a green, low-carbon way is crucial for the sustainable
development of modern society. Enzyme-photo-coupled catalytic systems (EPCS) that …