[HTML][HTML] Impact of gastrointestinal physiology on drug absorption in special populations––An UNGAP review

C Stillhart, K Vučićević, P Augustijns, AW Basit… - European Journal of …, 2020 - Elsevier
The release and absorption profile of an oral medication is influenced by the
physicochemical properties of the drug and its formulation, as well as by the anatomy and …

Relationships between gastric emptying, postprandial glycemia, and incretin hormones

CS Marathe, CK Rayner, KL Jones… - Diabetes care, 2013 - diabetesjournals.org
The importance of achieving tight glycemic control, usually assessed by glycated
hemoglobin (HbA1c), for both the prevention and delay in the progression of diabetes …

Gastric per-oral endoscopic myotomy (G-POEM) for refractory gastroparesis: results from an international prospective trial

K Vosoughi, Y Ichkhanian, P Benias, L Miller… - Gut, 2022 - gut.bmj.com
Objective Although gastric per-oral endoscopic myotomy (G-POEM) is considered a
promising technique for the management of refractory gastroparesis, high-quality evidence …

Epidemiology and outcomes of gastroparesis, as documented in general practice records, in the United Kingdom

Y Ye, B Jiang, S Manne, PL Moses, C Almansa… - Gut, 2021 - gut.bmj.com
Objective To generate real-world evidence for the epidemiology of gastroparesis in the UK,
we evaluated the prevalence, incidence, patient characteristics and outcomes of …

Gastric emptying and glycaemia in health and diabetes mellitus

LK Phillips, AM Deane, KL Jones, CK Rayner… - Nature Reviews …, 2015 - nature.com
The rate of gastric emptying is a critical determinant of postprandial glycaemia and,
accordingly, is fundamental to maintaining blood glucose homeostasis. Disordered gastric …

Carbon monoxide, hydrogen sulfide, and nitric oxide as signaling molecules in the gastrointestinal tract

G Farrugia, JH Szurszewski - Gastroenterology, 2014 - Elsevier
Carbon monoxide (CO) and hydrogen sulfide (H 2 S) used to be thought of simply as lethal
and (for H 2 S) smelly gaseous molecules; now they are known to have important signaling …

Abnormal initiation and conduction of slow-wave activity in gastroparesis, defined by high-resolution electrical map**

G O'Grady, TR Angeli, P Du, C Lahr, WJEP Lammers… - Gastroenterology, 2012 - Elsevier
BACKGROUND & AIMS: Interstitial cells of Cajal (ICC) generate slow waves. Disrupted ICC
networks and gastric dysrhythmias are each associated with gastroparesis. However, there …

Lymphatic vessels at the heart of the matter

V Angeli, NL Harvey - Cell Metabolism, 2015 - cell.com
Emergent research in the past decades has brought to light the importance of lymphatic
vessels in tissue homeostasis, immunity, metabolism, and inflammation. In Nature, Klotz et …

Chemical constituents and pharmacological actions of carob pods and leaves (Ceratonia siliqua L.) on the gastrointestinal tract: A review

K Rtibi, S Selmi, D Grami, M Amri, B Eto… - Biomedicine & …, 2017 - Elsevier
Carob tree, Ceratonia siliqua L., is a medicinal plant used in Tunisian traditional medicine
for the treatment of the gastro-intestinal (GI) disorders. In this respect, a relatively large …

Heart rate variability

G Ernst - 2014 - Springer
Organisms have rhythms, such as the rhythms of the cardiac and respiratory systems,
endocrinological networks, brain circuits, awake–sleep rhythms, and so on. All these …