Antiviral lectins: Selective inhibitors of viral entry

CA Mitchell, K Ramessar, BR O'Keefe - Antiviral research, 2017 - Elsevier
Many natural lectins have been reported to have antiviral activity. As some of these have
been put forward as potential development candidates for preventing or treating viral …

Cyanobacterial lectins characteristics and their role as antiviral agents

RS Singh, AK Walia, JS Khattar, DP Singh… - International Journal of …, 2017 - Elsevier
Lectins are ubiquitous proteins/glycoproteins of non-immune origin that bind reversibly to
carbohydrates in non-covalent and highly specific manner. These lectin-glycan interactions …

Organic electrochemical transistors for the detection of cell surface glycans

L Chen, Y Fu, N Wang, A Yang, Y Li, J Wu… - … applied materials & …, 2018 - ACS Publications
Cell surface glycans play critical roles in diverse biological processes, such as cell–cell
communication, immunity, infection, development, and differentiation. Their expressions are …

Reusable and dual-potential responses electrogenerated chemiluminescence biosensor for synchronously cytosensing and dynamic cell surface N-glycan evaluation

Y He, J Li, Y Liu - Analytical chemistry, 2015 - ACS Publications
A novel reusable and dual-potential responsive electrogenerated chemiluminescence (ECL)
biosensor was fabricated for synchronous detection of cancer cells and their surface N …

Ultrasensitive photoelectrochemical biosensing of cell surface N-glycan expression based on the enhancement of nanogold-assembled mesoporous silica amplified …

S Ge, F Lan, L Liang, N Ren, L Li, H Liu… - … Applied Materials & …, 2017 - ACS Publications
An ultrasensitive photoelectrochemical (PEC) biosensor for N-glycan expression based on
the enhancement of nanogold-assembled mesoporous silica nanoparticles (GMSNs) was …

Recent advances in measuring the kinetics of biomolecules by NMR relaxation dispersion spectroscopy

D Ban, CA Smith, BL de Groot, C Griesinger… - Archives of biochemistry …, 2017 - Elsevier
Protein function can be modulated or dictated by the amplitude and timescale of
biomolecular motion, therefore it is imperative to study protein dynamics. Nuclear Magnetic …

Integrating 19F Distance Restraints for Accurate Protein Structure Determination by Magic Angle Spinning NMR Spectroscopy

BR Runge, R Zadorozhnyi, CM Quinn… - Journal of the …, 2024 - ACS Publications
Traditional protein structure determination by magic angle spinning (MAS) solid-state NMR
spectroscopy primarily relies on interatomic distances up to 8 Å, extracted from 13C-, 15N …

Paper analytical devices for dynamic evaluation of cell surface N-glycan expression via a bimodal biosensor based on multibranched hybridization chain reaction …

L Liang, F Lan, L Li, S Ge, J Yu, N Ren, H Liu… - Biosensors and …, 2016 - Elsevier
A novel colorimetric/fluorescence bimodal lab-on-paper cyto-device was fabricated based
on concanavalin A (Con A)-integrating multibranched hybridization chain reaction (mHCR) …

Lectins engineered to favor a glycan-binding conformation have enhanced antiviral activity

Y Matoba, Y Sato, K Oda, Y Hatori… - Journal of Biological …, 2021 - ASBMB
Homologues of the Oscillatoria agardhii agglutinin (OAA) lectins contain a sequence repeat
of∼ 66 amino acids, with the number of tandem repeats varying across family members …

Toward closing the gap: quantum mechanical calculations and experimentally measured chemical shifts of a microcrystalline lectin

M Fritz, CM Quinn, M Wang, G Hou, X Lu… - The Journal of …, 2017 - ACS Publications
NMR chemical shifts are exquisitely sensitive probes for conformation and dynamics in
molecules and supramolecular assemblies. Although isotropic chemical shifts are easily …