Clinical translation of long-acting drug delivery formulations

W Li, J Tang, D Lee, TR Tice… - Nature Reviews …, 2022 - nature.com
Most pharmaceuticals are given using short-acting formulations that require frequent
administration, which can negatively affect patient compliance and increase failure risks …

Stereochemical enhancement of polymer properties

JC Worch, H Prydderch, S Jimaja, P Bexis… - Nature Reviews …, 2019 - nature.com
The importance of stereochemistry to the function of molecules is generally well understood.
However, to date, control over stereochemistry and its potential to influence properties of the …

Poly (lactic acid) stereocomplexes: A decade of progress

H Tsuji - Advanced drug delivery reviews, 2016 - Elsevier
Upon blending enantiomeric poly (l-lactide)[ie, poly (l-lactic acid)(PLLA)] and poly (d-
lactide)(PDLA)[ie, poly (d-lactic acid)(PDLA)] or synthesis of stereo block poly (lactide)[ie …

[HTML][HTML] Poly (lactic acid) stereocomplexes based molecular architectures: Synthesis and crystallization

RM Michell, V Ladelta, E Da Silva, AJ Müller… - Progress in Polymer …, 2023 - Elsevier
This review presents the state of the art of complex macromolecular architectures based on
polylactide stereocomplexes (PLA-sc) from the viewpoint of synthesis and crystallization …

Recent progress in using stereocomplexation for enhancement of thermal and mechanical property of polylactide

BH Tan, JK Muiruri, Z Li, C He - ACS Sustainable Chemistry & …, 2016 - ACS Publications
Polylactide (PLA) has been receiving significant attention in biopolymer research due to its
excellent biodegradability, biocompatibility and sustainability. The mass production of PLA …

Recent advances in processing of stereocomplex‐type polylactide

H Bai, S Deng, D Bai, Q Zhang… - Macromolecular Rapid …, 2017 - Wiley Online Library
Over the past two decades, biomass‐derived and biodegradable polylactide (PLA) has
sparked tremendous attention as a sustainable alternative to traditional petroleum‐derived …

Role of chain entanglements in the stereocomplex crystallization between poly (lactic acid) enantiomers

C Sun, Y Zheng, S Xu, L Ni, X Li, G Shan… - ACS Macro …, 2021 - ACS Publications
Stereocomplex (SC) crystallization between polymer enantiomers has opened a promising
avenue for preparing high-performance materials. However, high-crystallinity SCs are …

Toward Supertough and Heat-Resistant Stereocomplex-Type Polylactide/Elastomer Blends with Impressive Melt Stability via in Situ Formation of Graft Copolymer …

S Deng, H Bai, Z Liu, Q Zhang, Q Fu - Macromolecules, 2019 - ACS Publications
Stereocomplexation of enantiomeric poly (l-lactide)/poly (d-lactide)(PLLA/PDLA) chains
opens up a great opportunity toward sustainable PLA engineering plastic with exceptional …

Poisoning by purity: what stops stereocomplex crystallization in polylactide racemate?

J Cui, SG Yang, Q Zhang, F Liu, G Ungar - Macromolecules, 2023 - ACS Publications
Formation of stereocomplex crystals (SC) is an effective way to improve the heat resistance
and mechanical performance of poly (lactic acid) products. However, at all but the slowest …

Tammann analysis of the molecular weight selection of polymorphic crystal nucleation in symmetric racemic poly (lactic acid) blends

Y He, D Liu, J Wang, P Pan, W Hu - Macromolecules, 2022 - ACS Publications
High molecular weights switch the harvests of crystallinity from stereocomplex crystals to
homocrystals in the symmetric racemic poly (lactic acid)(PLA) blends. We performed Flash …