Incidence and persistence of psychotic experiences in the general population: systematic review and meta-analysis
Abstract Background and Hypothesis Psychotic experiences (PEs) are associated with
increased risk for mental disorders, in particular persistent PEs. PEs therefore might be …
increased risk for mental disorders, in particular persistent PEs. PEs therefore might be …
A review of default mode network connectivity and its association with social cognition in adolescents with autism spectrum disorder and early-onset psychosis
Recent studies have demonstrated substantial phenotypic overlap, notably social
impairment, between autism spectrum disorder (ASD) and schizophrenia. However, the …
impairment, between autism spectrum disorder (ASD) and schizophrenia. However, the …
EPA guidance on assessment of negative symptoms in schizophrenia
BackgroundDuring the last decades, a renewed interest for negative symptoms (NS) was
brought about by the increased awareness that they interfere severely with real-life …
brought about by the increased awareness that they interfere severely with real-life …
Effect of occupational health and safety on employee performance in the ghanaian construction sector
The contribution of the construction sector to the socio-economic development of Ghana
cannot be underestimated. However, these benefits are not without challenges such as …
cannot be underestimated. However, these benefits are not without challenges such as …
A review of negative symptom assessment strategies in youth at clinical high-risk for psychosis
Studies attempting to deconstruct the heterogeneity of schizophrenia and the attenuated
psychosis syndrome consistently find that negative symptoms are a core dimension that is …
psychosis syndrome consistently find that negative symptoms are a core dimension that is …
Updated perspectives on the clinical significance of negative symptoms in patients with schizophrenia
Introduction Negative symptoms in schizophrenia are associated with poor response to
available treatments, poor quality of life, and functional outcome. Therefore, they represent a …
available treatments, poor quality of life, and functional outcome. Therefore, they represent a …
Negative symptoms in children and adolescents with early-onset psychosis and at clinical high-risk for psychosis: systematic review and meta-analysis
Background Early-onset psychosis (EOP) refers to the development of a first episode of
psychosis before 18 years of age. Individuals at clinical high risk for psychosis (CHR-P) …
psychosis before 18 years of age. Individuals at clinical high risk for psychosis (CHR-P) …
Environmental enrichment or selective activation of parvalbumin-expressing interneurons ameliorates synaptic and behavioral deficits in animal models with …
Synaptic deficit-induced excitation and inhibition (E/I) imbalance have been implicated in the
pathogenesis of schizophrenia. Using in vivo two-photon microscopy, we examined the …
pathogenesis of schizophrenia. Using in vivo two-photon microscopy, we examined the …
Negative symptoms and functioning in youth at risk of psychosis: a systematic review and meta-analysis
Aim Youth at CHR for psychosis often demonstrate significant negative symptoms and poor
functioning, though the magnitude and direction of the relationship between the two remains …
functioning, though the magnitude and direction of the relationship between the two remains …
Prediction of conversion to psychosis in individuals with an at-risk mental state: a brief update on recent developments
Prediction of psychosis is already possible with an excellent prognostic performance based
on clinical assessments. Recent studies show that this accuracy can be further improved by …
on clinical assessments. Recent studies show that this accuracy can be further improved by …