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Epilepsy and brain network hubs
Epilepsy is a disorder of brain networks. A better understanding of structural and dynamic
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …
network properties may improve epilepsy diagnosis, treatment, and prognostics. Hubs are …
[HTML][HTML] Recent advances in neuroimaging of epilepsy
Human neuroimaging has had a major impact on the biological understanding of epilepsy
and the relationship between pathophysiology, seizure management, and outcomes. This …
and the relationship between pathophysiology, seizure management, and outcomes. This …
Identification of different MRI atrophy progression trajectories in epilepsy by subtype and stage inference
Artificial intelligence (AI)-based tools are widely employed, but their use for diagnosis and
prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional …
prognosis of neurological disorders is still evolving. Here we analyse a cross-sectional …
Thalamic deep brain stimulation modulates cycles of seizure risk in epilepsy
Chronic brain recordings suggest that seizure risk is not uniform, but rather varies
systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human …
systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human …
A shifting role of thalamocortical connectivity in the emergence of cortical functional organization
The cortical patterning principle has been a long-standing question in neuroscience, yet
how this translates to macroscale functional specialization in the human brain remains …
how this translates to macroscale functional specialization in the human brain remains …
Improving the prediction of epilepsy surgery outcomes using basic scalp EEG findings
Objective This study aims to evaluate the role of scalp electroencephalography (EEG; ictal
and interictal patterns) in predicting resective epilepsy surgery outcomes. We use the data to …
and interictal patterns) in predicting resective epilepsy surgery outcomes. We use the data to …
Focal to bilateral tonic–clonic seizures are associated with widespread network abnormality in temporal lobe epilepsy
Objective Our objective was to identify whether the whole‐brain structural network
alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic–clonic …
alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic–clonic …
Disorganization of language and working memory systems in frontal versus temporal lobe epilepsy
Cognitive impairment is a common comorbidity of epilepsy and adversely impacts people
with both frontal lobe (FLE) and temporal lobe (TLE) epilepsy. While its neural substrates …
with both frontal lobe (FLE) and temporal lobe (TLE) epilepsy. While its neural substrates …
A phase 1 open‐label trial evaluating focused ultrasound unilateral anterior thalamotomy for focal onset epilepsy
Objective Focused ultrasound ablation (FUSA) is an emerging treatment for neurological
and psychiatric diseases. We describe the initial experience from a pilot, open‐label, single …
and psychiatric diseases. We describe the initial experience from a pilot, open‐label, single …
Episodic memory network connectivity in temporal lobe epilepsy
Objective Temporal lobe epilepsy (TLE) affects brain networks and is associated with
impairment of episodic memory. Temporal and extratemporal reorganization of memory …
impairment of episodic memory. Temporal and extratemporal reorganization of memory …