Exploring regulatory mechanisms on miRNAs and their implications in inflammation-related diseases
E Nalbant, YZ Akkaya-Ulum - Clinical and experimental medicine, 2024 - Springer
This comprehensive exploration delves into the pivotal role of microRNAs (miRNAs) within
the intricate tapestry of cellular regulation. As potent orchestrators of gene expression …
the intricate tapestry of cellular regulation. As potent orchestrators of gene expression …
MicroRNA-21 is a versatile regulator and potential treatment target in central nervous system disorders
X Bai, Z Bian - Frontiers in molecular neuroscience, 2022 - frontiersin.org
MicroRNAs (miRNAs) are a class of endogenous, non-coding, single-stranded RNAs with a
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
length of approximately 22 nucleotides that are found in eukaryotes. miRNAs are involved in …
Modulators of MicroRNA function in the immune system
Y Jia, Y Wei - International journal of molecular sciences, 2020 - mdpi.com
MicroRNAs (miRNAs) play a key role in fine-tuning host immune homeostasis and
responses through the negative regulation of mRNA stability and translation. The pathways …
responses through the negative regulation of mRNA stability and translation. The pathways …
[HTML][HTML] hPMSCs-Derived Exosomal miRNA-21 Protects Against Aging-Related Oxidative Damage of CD4+ T Cells by Targeting the PTEN/PI3K-Nrf2 Axis
Y **ong, Y **ong, H Zhang, Y Zhao, K Han… - Frontiers in …, 2021 - frontiersin.org
Mesenchymal stem cells (MSCs)-derived exosomes were considered a novel therapeutic
approach in many aging-related diseases. This study aimed to clarify the protective effects of …
approach in many aging-related diseases. This study aimed to clarify the protective effects of …
[HTML][HTML] Small non-coding RNAs as important players, biomarkers and therapeutic targets in multiple sclerosis: A comprehensive overview
Multiple sclerosis (MS) is a leading cause of progressive disability among young adults
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …
caused by inflammation, demyelination and axonal loss in the central nervous system. Small …
Aberrant DNA methylation profile exacerbates inflammation and neurodegeneration in multiple sclerosis patients
N Celarain, J Tomas-Roig - Journal of neuroinflammation, 2020 - Springer
Multiple sclerosis (MS) is an autoimmune and demyelinating disease of the central nervous
system characterised by incoordination, sensory loss, weakness, changes in bladder …
system characterised by incoordination, sensory loss, weakness, changes in bladder …
Whole-blood methylation signatures are associated with and accurately classify multiple sclerosis disease severity
Background The variation in multiple sclerosis (MS) disease severity is incompletely
explained by genetics, suggesting genetic and environmental interactions are involved …
explained by genetics, suggesting genetic and environmental interactions are involved …
MicroRNAs, multiple sclerosis, and depression
H Wang - International Journal of Molecular Sciences, 2021 - mdpi.com
Multiple sclerosis (MS) is a chronic disease of the central nervous system that affects the
brain and spinal cord. There are several disease courses in MS including relapsing …
brain and spinal cord. There are several disease courses in MS including relapsing …
Combining evidence from four immune cell types identifies DNA methylation patterns that implicate functionally distinct pathways during Multiple Sclerosis progression
Abstract Background Multiple Sclerosis (MS) is a chronic inflammatory disease and a
leading cause of progressive neurological disability among young adults. DNA methylation …
leading cause of progressive neurological disability among young adults. DNA methylation …
Evaluation of cell-specific epigenetic age acceleration in people with multiple sclerosis
Background and Objectives In multiple sclerosis (MS), accelerated aging of the immune
system (immunosenescence) may be associated with disease onset or drive progression …
system (immunosenescence) may be associated with disease onset or drive progression …