Inflammatory pain is the most common type of pain that is treated clinically. The use of
currently available treatments (classic analgesics-NSAIDs, paracetamol and opioids) is …

This paper is the thirty-sixth consecutive installment of the annual review of research
concerning the endogenous opioid system. It summarizes papers published during 2013 …

Pain, a severely debilitating symptom of many human disorders, is a growing, unmet
biomedical problem. Although the use of zebrafish (Danio rerio) to investigate both …

Purpose Commonly used nonopioid analgesic agents that are incorporated into multimodal
perioperative pain management protocols in spinal surgery are reviewed. Summary Spinal …

Background Cancer pain is complex, and despite the introduction of the WHO cancer pain
ladder, few studies have looked at the prevalence of adjuvant medication use in an inpatient …

Lectins are proteins that bind to specific mono-or oligosaccharides. This study aimed to
evaluate the antinociceptive and anti-inflammatory effects of the lectin from the red marine …

The present study aimed to design and synthesize a new series of hybrid compounds with
pyrrolidine-2, 5-dione and thiophene rings in the structure as potential anticonvulsant and …

Analgesic drugs in a combination-form can achieve greater efficacy with lesser side effects
compared to either drug alone. The combination of drugs acting at different targets or …

Background Panax stipuleanatus represents a folk medicine for treatment of inflammation.
However, lack of experimental data does not confirm its function. This article aims to …

Alternate forms of drug crystals display different physicochemical properties. These include
stability, dissolution rate, bioavailability and solubility, which can affect pharmacokinetics …