Blue-light receptors for optogenetics
Sensory photoreceptors underpin light-dependent adaptations of organismal physiology,
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …
development, and behavior in nature. Adapted for optogenetics, sensory photoreceptors …
LOV-based optogenetic devices: light-driven modules to impart photoregulated control of cellular signaling
The Light-Oxygen-Voltage domain family of proteins is widespread in biology where they
impart sensory responses to signal transduction domains. The small, light responsive LOV …
impart sensory responses to signal transduction domains. The small, light responsive LOV …
Function, structure and mechanism of bacterial photosensory LOV proteins
J Herrou, S Crosson - Nature reviews microbiology, 2011 - nature.com
LOV (light, oxygen or voltage) domains are protein photosensors that are conserved in
bacteria, archaea, plants and fungi, and detect blue light via a flavin cofactor. LOV domains …
bacteria, archaea, plants and fungi, and detect blue light via a flavin cofactor. LOV domains …
The evolution of flavin-binding photoreceptors: an ancient chromophore serving trendy blue-light sensors
Photoreceptor flavoproteins of the LOV, BLUF, and cryptochrome families are ubiquitous
among the three domains of life and are configured as UVA/blue-light systems not only in …
among the three domains of life and are configured as UVA/blue-light systems not only in …
LOV to BLUF: flavoprotein contributions to the optogenetic toolkit
JM Christie, J Gawthorne, G Young, NJ Fraser, AJ Roe - Molecular plant, 2012 - cell.com
Optogenetics is an emerging field that combines optical and genetic approaches to non-
invasively interfere with cellular events with exquisite spatiotemporal control. Although it …
invasively interfere with cellular events with exquisite spatiotemporal control. Although it …
Old Chromophores, New Photoactivation Paradigms, Trendy Applications: Flavins in Blue Light‐Sensing Photoreceptors†
The knowledge on the mechanisms by which blue light (BL) is sensed by diverse and
numerous organisms, and of the physiological responses elicited by the BL photoreceptors …
numerous organisms, and of the physiological responses elicited by the BL photoreceptors …
Rational design of an efficient, genetically encodable, protein-encased singlet oxygen photosensitizer
Singlet oxygen, O2 (a1Δg), plays a key role in many processes of cell signaling. Limitations
in mechanistic studies of such processes are generally associated with the difficulty of …
in mechanistic studies of such processes are generally associated with the difficulty of …
Optogenetic control of cell function using engineered photoreceptors
Over the past decades, there has been growing recognition that light can provide a powerful
stimulus for biological interrogation. Light‐actuated tools allow manipulation of molecular …
stimulus for biological interrogation. Light‐actuated tools allow manipulation of molecular …
Structure and function of the ZTL/FKF1/LKP2 group proteins in Arabidopsis
Abstract The ZTL/FKF1/LKP2 group proteins are LOV-domain-based blue-light
photoreceptors that control protein degradation by ubiquitination. These proteins were …
photoreceptors that control protein degradation by ubiquitination. These proteins were …
Blue light-induced dimerization of a bacterial LOV–HTH DNA-binding protein
With their utilization of light-driven allostery to control biochemical activities, photosensory
proteins are of great interest as model systems and novel reagents for use by the basic …
proteins are of great interest as model systems and novel reagents for use by the basic …