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Design automation in synthetic biology
Design automation refers to a category of software tools for designing systems that work
together in a workflow for designing, building, testing, and analyzing systems with a target …
together in a workflow for designing, building, testing, and analyzing systems with a target …
Genetic circuit design automation
INTRODUCTION Cells respond to their environment, make decisions, build structures, and
coordinate tasks. Underlying these processes are computational operations performed by …
coordinate tasks. Underlying these processes are computational operations performed by …
Genetic circuit design automation for the gut resident species Bacteroides thetaiotaomicron
Bacteroides thetaiotaomicron is a human-associated bacterium that holds promise for
delivery of therapies in the gut microbiome. Therapeutic bacteria would benefit from the …
delivery of therapies in the gut microbiome. Therapeutic bacteria would benefit from the …
Programming Escherichia coli to function as a digital display
Synthetic genetic circuits offer the potential to wield computational control over biology, but
their complexity is limited by the accuracy of mathematical models. Here, we present …
their complexity is limited by the accuracy of mathematical models. Here, we present …
Precision design of stable genetic circuits carried in highly‐insulated E. coli genomic landing pads
Genetic circuits have many applications, from guiding living therapeutics to ordering process
in a bioreactor, but to be useful they have to be genetically stable and not hinder the host …
in a bioreactor, but to be useful they have to be genetically stable and not hinder the host …
The Synthetic Biology Open Language (SBOL) version 3: simplified data exchange for bioengineering
The Synthetic Biology Open Language (SBOL) is a community-developed data standard that
allows knowledge about biological designs to be captured using a machine-tractable …
allows knowledge about biological designs to be captured using a machine-tractable …
Sharing structure and function in biological design with SBOL 2.0
The Synthetic Biology Open Language (SBOL) is a standard that enables collaborative
engineering of biological systems across different institutions and tools. SBOL is developed …
engineering of biological systems across different institutions and tools. SBOL is developed …
The automated Galaxy-SynBioCAD pipeline for synthetic biology design and engineering
Here we introduce the Galaxy-SynBioCAD portal, a toolshed for synthetic biology, metabolic
engineering, and industrial biotechnology. The tools and workflows currently shared on the …
engineering, and industrial biotechnology. The tools and workflows currently shared on the …
Discovering design principles for biological functionalities: Perspectives from systems biology
Network architecture plays a crucial role in governing the dynamics of any biological
network. Further, network structures have been shown to remain conserved across …
network. Further, network structures have been shown to remain conserved across …
Galaxy-SynBioCAD: Automated Pipeline for Synthetic Biology Design and Engineering
Abstract We introduce the Galaxy-SynBioCAD portal, the first toolshed for synthetic biology,
metabolic engineering, and industrial biotechnology. The tools and workflows currently …
metabolic engineering, and industrial biotechnology. The tools and workflows currently …