Simple Summary Given its huge impact on global health, lung cancer remains a major
diagnostic and therapeutic challenge. However, much has been achieved, and this review …

A steady dysfunctional state caused by chronic antigen stimulation in the tumor
microenvironment (TME) is known as CD8+ T cell exhaustion. Exhausted-like CD8+ T cells …

The past decade has witnessed a revolution in cancer treatment, shifting from conventional
drugs (chemotherapies) towards targeted molecular therapies and immune-based …

Stage IV nonsmall cell lung cancer (NSCLC) is a heterogeneous group of patients for whom
systemic therapy is decided based on tumour-biological cancer features (histology, PD-L1 …

Abstract Immunotherapy with PD-1/PD-L1 inhibitors is the standard method of care for the
treatment of newly diagnosed advanced or metastatic NSCLC, with or without …

Background Chronic obstructive pulmonary disease (COPD) is a prevalent condition that
significantly impacts public health. Unfortunately, there are few effective treatment options …

Non-Small Cell Lung Cancer (NSCLC) management remains a formidable challenge in the
field of oncology, representing a significant global health burden. However, recent years …

Gene therapy has long been a cornerstone in the treatment of rare diseases and genetic
disorders, offering targeted solutions to conditions once considered untreatable. As the field …

Non-small cell lung carcinoma (NSCLC) comprises the majority of lung cancer cases,
characterized by a complex interplay of genetic alterations, environmental factors, and …

CAR-T cell therapies have been successful in treating numerous hematologic malignancies
as the T cell can be engineered to target a specific antigen associated with the disease …