The halogen bond occurs when there is evidence of a net attractive interaction between an
electrophilic region associated with a halogen atom in a molecular entity and a nucleophilic …

Plasmodium sporozoites are the product of a complex developmental process in the
mosquito vector and are destined to infect the mammalian liver. Attention has been drawn to …

Clove essential oil (CEO) was extracted from dried clove buds using distillation. Gas
chromatography–mass spectrometer confirmed eugenol was the main component of CEO …

Chemogenetic characterization through in vitro evolution combined with whole-genome
analysis can identify antimalarial drug targets and drug-resistance genes. We performed a …

Plasmodium spp parasites harbor an unusual plastid organelle called the apicoplast. Due to
its prokaryotic origin and essential function, the apicoplast is a key target for development of …

Halogen bonding has been extensively described in the context of a variety of self-
assembled supramolecular systems and efficiently utilized in the rational design of materials …

The malaria parasite, Plasmodium falciparum, harbours a relict plastid known as the
'apicoplast'. The discovery of the apicoplast ushered in an exciting new prospect for drug …

Malaria, which is caused by Plasmodium spp., starts with an asymptomatic phase, during
which sporozoites, the parasite form that is injected into the skin by a mosquito, develop into …

In their infection cycle, malaria parasites undergo replication and population expansions
within the vertebrate host and the mosquito vector. Host infection initiates with sporozoite …

A family of apicomplexa-specific proteins containing AP2 DNA-binding domains (ApiAP2s)
was identified in malaria parasites. This family includes sequence-specific transcription …