Unraveling the mechanobiology of cornea: From bench side to the clinic

S Yang, J Zhang, Y Tan, Y Wang - Frontiers in bioengineering and …, 2022 - frontiersin.org
The cornea is a transparent, dome-shaped structure on the front part of the eye that serves
as a major optic element and a protector from the external environment. Recent evidence …

Biomechanical homeostasis in ocular diseases: A mini-review

Y Cheng, T Ren, N Wang - Frontiers in Public Health, 2023 - frontiersin.org
Diabetes mellitus-induced hyperglycemia is responsible for multiple pathological ocular
alternations from vasculopathy to biomechanical dyshomeostasis. Biomechanical …

Higher intraocular pressure is associated with slower axial growth in children with non-pathological high myopia

FSL Yii, M He, F Chappell, MO Bernabeu… - Eye, 2024 - nature.com
Objectives To investigate the association between intraocular pressure (IOP) and axial
elongation rate in highly myopic children from the ZOC-BHVI High Myopia Cohort Study …

Comparison of two analyzer measurements focusing on material stiffness among normal, treatment-naïve, and treated glaucoma eyes

S Aoki, R Asaoka, Y Fu**o, S Nakakura, H Murata… - Scientific Reports, 2023 - nature.com
To investigate differences in biomechanical properties focusing on stiffness parameters
between normal, treatment-naïve primary open-angle glaucoma (POAG), and treated POAG …

Refractive associations with corneal biomechanical properties among young adults: a population-based Corvis ST study

DL Li, MX Liu, ZJ Yin, YZ Li, R Ma, YJ Zheng… - Graefe's Archive for …, 2024 - Springer
Purpose To assess the associations of corneal biomechanical properties as measured by
the Corvis ST with refractive errors and ocular biometry in an unselected sample of young …

Comparisons of the protein expressions between high myopia and moderate myopia on the anterior corneal stroma in human

W Wu, Y Xu, F Zhang - Graefe's Archive for Clinical and Experimental …, 2023 - Springer
Purpose To investigate the differentially expressed proteins (DEP) between high myopia
and moderate myopia on the anterior corneal stroma. Methods Tandem mass tag (TMT) …

Corneal metabolic biomarkers for moderate and high myopia in human

W Wu, Y Song, M Sun, Y Li, Y Xu, M Xu, Y Yang… - Experimental Eye …, 2023 - Elsevier
This study aimed to identify the corneal metabolic biomarkers for moderate and high myopia
in human. We enrolled 221 eyes from 221 subjects with myopia to perform the femtosecond …

Assessment of corneal biomechanics in anisometropia using Scheimpflug technology

R Gao, Y Ren, S Li, H Xu, X Lin… - … in Bioengineering and …, 2022 - frontiersin.org
Purpose: To investigate the relationship between corneal biomechanical and ocular
biometric parameters, and to explore biomechanical asymmetry between anisometropic …

Corneal biomechanics are not exclusively compromised in high myopia

F Yii, N Strang, MO Bernabeu, B Dhillon… - Ophthalmic and …, 2024 - Wiley Online Library
Introduction Research assuming linearity has concluded that corneal biomechanics are
compromised in high myopia. We investigated whether this assumption was appropriate and …

Effect of corneal stiffness decrease on axial length elongation in myopia determined based on a mathematical estimation model

Q Ren, Z Chu, W Cui, L Cheng, W Su… - … in Bioengineering and …, 2023 - frontiersin.org
Purpose: To investigate the relationship between the corneal material stiffness parameter
stress-strain index (SSI) and axial length (AL) elongation with varying severities of myopia …