The Effect of Nanoparticle Size on In Vivo Pharmacokinetics and Cellular Interaction

N Hoshyar, S Gray, H Han, G Bao - Nanomedicine, 2016 - Taylor & Francis
Nanoparticle-based technologies offer exciting new approaches to disease diagnostics and
therapeutics. To take advantage of unique properties of nanoscale materials and structures …

[HTML][HTML] Application of nanoparticles in cancer treatment: a concise review

M Sell, AR Lopes, M Escudeiro, B Esteves… - Nanomaterials, 2023 - mdpi.com
Timely diagnosis and appropriate antitumoral treatments remain of utmost importance, since
cancer remains a leading cause of death worldwide. Within this context, nanotechnology …

Frontiers in cancer nanomedicine: directing mass transport through biological barriers

M Ferrari - Trends in biotechnology, 2010 - cell.com
The physics of mass transport within body compartments and across biological barriers
differentiates cancers from healthy tissues. Variants of nanoparticles can be manufactured in …

Physico-chemical parameters that govern nanoparticles fate also dictate rules for their molecular evolution

S Dufort, L Sancey, JL Coll - Advanced drug delivery reviews, 2012 - Elsevier
Nanoparticles are efficient to safely deliver therapeutic and imaging contrast agents to
tumors for cancer diagnostic and therapy, if they can escape the reticuloendothelial system …

Discoidal porous silicon particles: fabrication and biodistribution in breast cancer bearing mice

B Godin, C Chiappini, S Srinivasan… - Advanced functional …, 2012 - Wiley Online Library
Porous silicon (pSi) is emerging as a promising material in the development of nanovectors
for the systemic delivery of therapeutic and imaging agents. The integration of …

Polymeric micelles as mighty nanocarriers for cancer gene therapy: a review

M Yousefpour Marzbali… - Cancer chemotherapy and …, 2017 - Springer
Purpose Gene therapy has shown extensive potential to treat human diseases occurring
from the defection of genes like various types of cancers. The cationic polymers, as non-viral …

Multistage nanovectors: from concept to novel imaging contrast agents and therapeutics

B Godin, E Tasciotti, X Liu, RE Serda… - Accounts of chemical …, 2011 - ACS Publications
Over the last few decades a great variety of nanotechnology based platforms have been
synthesized and fabricated to improve the delivery of active compounds to a disease site …

Mechanisms of cooperation in cancer nanomedicine: towards systems nanotechnology

S Hauert, SN Bhatia - Trends in biotechnology, 2014 - cell.com
Nanoparticles are designed to deliver therapeutics and diagnostics selectively to tumors.
Their size, shape, charge, material, coating, and cargo determine their individual …

Mathematical modeling of coupled drug and drug-encapsulated nanoparticle transport in patient-specific coronary artery walls

SS Hossain, SFA Hossainy, Y Bazilevs, VM Calo… - Computational …, 2012 - Springer
The majority of heart attacks occur when there is a sudden rupture of atherosclerotic plaque,
exposing prothrombotic emboli to coronary blood flow, forming clots that can cause …

Enhanced uptake and transport of PLGA-modified nanoparticles in cervical cancer

LB Sims, LT Curtis, HB Frieboes… - Journal of …, 2016 - Springer
Background Uncoordinated cellular proliferation and dysregulated angiogenesis in solid
tumors are coupled with inadequate tissue, blood, and lymphatic vascularization …