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PLGA particles in immunotherapy
D Horvath, M Basler - Pharmaceutics, 2023 - mdpi.com
Poly (lactic-co-glycolic acid)(PLGA) particles are a widely used and extensively studied drug
delivery system. The favorable properties of PLGA such as good bioavailability, controlled …
delivery system. The favorable properties of PLGA such as good bioavailability, controlled …
Recent research and development of PLGA/PLA microspheres/nanoparticles: A review in scientific and industrial aspects
F Qi, J Wu, H Li, G Ma - Frontiers of Chemical Science and Engineering, 2019 - Springer
Abstract Poly (D, L-lactic-co-glycolic acid)(PLGA)/poly (lactic acid)(PLA) microspheres/
nanoparticles are one of the most successful drug delivery systems (DDS) in lab and clinic …
nanoparticles are one of the most successful drug delivery systems (DDS) in lab and clinic …
Overview on therapeutic applications of microparticulate drug delivery systems
Research in novel drug delivery systems is being explored competitively in order to attain
maximum therapeutic effect while minimizing the adverse effects. Despite several …
maximum therapeutic effect while minimizing the adverse effects. Despite several …
Harnessing Dendritic Cells for Poly (D,L-lactide-co-glycolide) Microspheres (PLGA MS)—Mediated Anti-tumor Therapy
J Koerner, D Horvath, M Groettrup - Frontiers in immunology, 2019 - frontiersin.org
With emerging success in fighting off cancer, chronic infections, and autoimmune diseases,
immunotherapy has become a promising therapeutic approach compared to conventional …
immunotherapy has become a promising therapeutic approach compared to conventional …
[HTML][HTML] Nano-microparticle platforms in develo** next-generation vaccines
The first vaccines ever made were based on live-attenuated or inactivated pathogens, either
whole cells or fragments. Although these vaccines required the co-administration of antigens …
whole cells or fragments. Although these vaccines required the co-administration of antigens …
Multiantigenic nanoformulations activate anticancer immunity depending on size
S Li, X Feng, J Wang, W Xu, MA Islam… - Advanced Functional …, 2019 - Wiley Online Library
Nanoparticle‐adjuvanted cancer vaccines are attracting increasing attention because they
can induce an effective anticancer immune response. Single‐antigen vaccines are …
can induce an effective anticancer immune response. Single‐antigen vaccines are …
[HTML][HTML] Technological approaches for improving vaccination compliance and coverage
Vaccination has been well recognised as a critically important tool in preventing infectious
disease, yet incomplete immunisation coverage remains a major obstacle to achieving …
disease, yet incomplete immunisation coverage remains a major obstacle to achieving …
Old dog new tricks: PLGA microparticles as an adjuvant for insulin peptide fragment-induced immune tolerance against type 1 diabetes
M Liu, D Feng, X Liang, M Li, J Yang… - Molecular …, 2020 - ACS Publications
Poly [lactic-co-(glycolic acid)](PLGA) is arguably one of the most versatile synthetic
copolymers used for biomedical applications. In vivo delivery of multiple substances …
copolymers used for biomedical applications. In vivo delivery of multiple substances …
Overcoming immunogenicity issues of HIV p24 antigen by the use of innovative nanostructured lipid carriers as delivery systems: evidences in mice and non-human …
E Bayon, J Morlieras, N Dereuddre-Bosquet, A Gonon… - Npj Vaccines, 2018 - nature.com
HIV is one of the deadliest pandemics of modern times, having already caused 35 million
deaths around the world. Despite the huge efforts spent to develop treatments, the virus …
deaths around the world. Despite the huge efforts spent to develop treatments, the virus …
Adjuvanticity regulation by biodegradable polymeric nano/microparticle size
Polymeric nano/microparticles as vaccine adjuvants have been researched in experimental
and clinical studies. A more profound understanding of how the physicochemical properties …
and clinical studies. A more profound understanding of how the physicochemical properties …