C-reactive protein: a target for therapy to reduce inflammation

SA Rizo-Téllez, M Sekheri, JG Filep - Frontiers in immunology, 2023 - frontiersin.org
C-reactive protein (CRP) is well-recognized as a sensitive biomarker of inflammation.
Association of elevations in plasma/serum CRP level with disease state has received …

Stroke risk factors, genetics, and prevention

AK Boehme, C Esenwa, MSV Elkind - Circulation research, 2017 - ahajournals.org
Stroke is a heterogeneous syndrome, and determining risk factors and treatment depends
on the specific pathogenesis of stroke. Risk factors for stroke can be categorized as …

[HTML][HTML] Glutathione: A Samsonian life-sustaining small molecule that protects against oxidative stress, ageing and damaging inflammation

CA Labarrere, GS Kassab - Frontiers in nutrition, 2022 - frontiersin.org
Many local and systemic diseases especially diseases that are leading causes of death
globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart …

The clinical significance and potential role of C-reactive protein in chronic inflammatory and neurodegenerative diseases

Y Luan, Y Yao - Frontiers in immunology, 2018 - frontiersin.org
C-reactive protein (CRP) is an acute-phase protein synthesized by hepatocytes in response
to pro-inflammatory cytokines during inflammatory/infectious processes. CRP exists in …

C-reactive protein in atherothrombosis and angiogenesis

L Badimon, E Peña, G Arderiu, T Padró… - Frontiers in …, 2018 - frontiersin.org
C-reactive protein (CRP) is a short pentraxin mainly found as a pentamer in the circulation,
or as non-soluble monomers CRP (mCRP) in tissues, exerting different functions. This …

High-sensitivity C-reactive protein and cardiovascular disease: a resolute belief or an elusive link?

O Yousuf, BD Mohanty, SS Martin, PH Joshi… - Journal of the American …, 2013 - jacc.org
The role of inflammation in the propagation of atherosclerosis and susceptibility to
cardiovascular (CV) events is well established. Of the wide array of inflammatory biomarkers …

Platelets, inflammation and tissue regeneration

AT Nurden - Thrombosis and haemostasis, 2011 - thieme-connect.com
Blood platelets have long been recognised to bring about primary haemostasis with
deficiencies in platelet production and function manifesting in bleeding while upregulated …

Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke

CC Esenwa, MS Elkind - Nature Reviews Neurology, 2016 - nature.com
Proinflammatory conditions, including acute and chronic infections, have been associated
with an increased risk of stroke. The risk of stroke is increased by both the acute and chronic …

C-reactive protein and inflammation: conformational changes affect function

Y Wu, LA Potempa, D El Kebir, JG Filep - Biological chemistry, 2015 - degruyter.com
The prototypic acute-phase reactant C-reactive protein (CRP) has long been recognized as
a useful marker and gauge of inflammation. CRP also plays an important role in host …

C-reactive protein, immunothrombosis and venous thromboembolism

C Dix, J Zeller, H Stevens, SU Eisenhardt… - Frontiers in …, 2022 - frontiersin.org
C-reactive protein (CRP) is a member of the highly conserved pentraxin superfamily of
proteins and is often used in clinical practice as a marker of infection and inflammation …