Treatment landscape of triple-negative breast cancer—expanded options, evolving needs
Tumour heterogeneity and a long-standing paucity of effective therapies other than
chemotherapy have contributed to triple-negative breast cancer (TNBC) being the subtype …
chemotherapy have contributed to triple-negative breast cancer (TNBC) being the subtype …
Heterogeneity of triple negative breast cancer: Current advances in subty** and treatment implications
As the field of translational 'omics has progressed, refined classifiers at both genomic and
proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically …
proteomic levels have emerged to decipher the heterogeneity of breast cancer in a clinically …
Gender-specific impact of sex hormones on the immune system
F Sciarra, F Campolo, E Franceschini… - International journal of …, 2023 - mdpi.com
Sex hormones are key determinants of gender-related differences and regulate growth and
development during puberty. They also exert a broad range modulation of immune cell …
development during puberty. They also exert a broad range modulation of immune cell …
Targeting breast cancer: An overlook on current strategies
Breast cancer (BC) is one of the most widely diagnosed cancers and a leading cause of
cancer death among women worldwide. Globally, BC is the second most frequent cancer …
cancer death among women worldwide. Globally, BC is the second most frequent cancer …
CBP/p300: critical co-activators for nuclear steroid hormone receptors and emerging therapeutic targets in prostate and breast cancers
Simple Summary The CREB-binding protein (CBP) and p300 are paralogous lysine
acetyltransferases that serve as critical co-activators for transcription factors involved in …
acetyltransferases that serve as critical co-activators for transcription factors involved in …
Androgen receptor as an emerging feasible biomarker for breast cancer
CP You, MH Leung, WC Tsang, US Khoo, H Tsoi - Biomolecules, 2022 - mdpi.com
Biomarkers can be used for diagnosis, prognosis, and prediction in targeted therapy. The
estrogen receptor α (ERα) and human epidermal growth factor receptor 2 (HER2) are …
estrogen receptor α (ERα) and human epidermal growth factor receptor 2 (HER2) are …
[HTML][HTML] Targeting triple-negative breast cancer: A clinical perspective
LS Popovic, G Matovina-Brko, M Popovic… - Oncology …, 2023 - ncbi.nlm.nih.gov
Triple-negative breast cancer (TNBC) is a disease with often an aggressive course and a
poor prognosis compared to other subtypes of breast cancer. TNBC accounts for …
poor prognosis compared to other subtypes of breast cancer. TNBC accounts for …
Development of a Novel Amplifiable System to Quantify Hydrogen Peroxide in Living Cells
Although many redox signaling molecules are present at low concentrations, typically
ranging from micromolar to submicromolar levels, they often play essential roles in a wide …
ranging from micromolar to submicromolar levels, they often play essential roles in a wide …
What is the impact of sex hormones on the pathogenesis of rheumatoid arthritis?
C Raine, I Giles - Frontiers in Medicine, 2022 - frontiersin.org
Rheumatoid arthritis (RA) is the most common inflammatory rheumatic disease and has a
female predominance of around 3: 1. The relationship between sex hormones and RA has …
female predominance of around 3: 1. The relationship between sex hormones and RA has …
The androgen receptor is a therapeutic target in desmoplastic small round cell sarcoma
Desmoplastic small round cell tumor (DSRCT) is an aggressive, usually incurable sarcoma
subtype that predominantly occurs in post-pubertal young males. Recent evidence suggests …
subtype that predominantly occurs in post-pubertal young males. Recent evidence suggests …