The saccadic eye movement system provides researchers with a powerful tool with which to
explore the cognitive control of behaviour. It is a behavioural system whose limited output …

The increasing use of eye movement paradigms to assess the functional integrity of brain
systems involved in sensorimotor and cognitive processing in clinical disorders requires …

Background The COGS is a multi-site NIMH-sponsored investigation of the genetic basis of
12 primary and multiple secondary quantitative endophenotypes in schizophrenia. Methods …

The present study used functional magnetic resonance imaging (fMRI) to investigate the
neural mechanisms of nicotine effects on antisaccades (an oculomotor measure of the …

Many physiological and pathological changes in brain function manifest in eye-movement
control. As such, assessment of oculomotion is an invaluable part of a clinical examination …

The mechanisms that control eye movements in the antisaccade task are not fully
understood. One influential theory claims that the generation of antisaccades is dependent …

Rationale Human and animal studies over the last two decades report that nicotine can
improve cognitive performance. Prospective memory (PM), the retrieval and implementation …

Pre-frontal cortical (PFC) dysfunction has been put forward as the basis for development and
maintenance of addiction. To explore this relationship, the present study investigated the …

Nicotine alters cognitive processes that include working memory and long‐term memory.
Trace fear conditioning may involve working memory during acquisition while also allowing …

Background: Varenicline (VAR) is a partial nicotinic receptor agonist that is an effective
smoking cessation medication. Preliminary evidence indicates that it may also reduce …