Nanomedicine-based delivery strategies for breast cancer treatment and management

P Tagde, A Najda, K Nagpal, GT Kulkarni… - International journal of …, 2022 - mdpi.com
Breast cancer is one of the most common types of cancer among women globally. It is
caused by mutations in the estrogen/progesterone receptors and conventional treatment …

Decision making in older adults with cancer

C DuMontier, KP Loh… - Journal of Clinical …, 2021 - ascopubs.org
Significant progress has been made toward improving the care of older adults with cancer.
As described elsewhere in this Special Series, the evidence base in geriatric oncology has …

Geriatric assessment for the practicing clinician: The why, what, and how

A Magnuson, KP Loh, F Stauffer, W Dale… - CA: A Cancer …, 2024 - Wiley Online Library
Older adults with cancer heterogeneously experience health care, treatment, and symptoms.
Geriatric assessment (GA) offers a comprehensive evaluation of an older individual's health …

[HTML][HTML] Understanding treatment tolerability in older adults with cancer

MA Flannery, E Culakova, BE Canin… - Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
The treatment cannot be worse than the disease is an oft-cited statement representing the
important concept of tolerability; older patients often express concerns about side effects …

Low-intensity adjuvant chemotherapy for breast cancer in older women: results from the prospective multicenter HOPE trial

MS Sedrak, CL Sun, J Ji, HJ Cohen… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Older women with high-risk early breast cancer (EBC) benefit from adjuvant
chemotherapy, but their treatment is frequently complicated by toxic side effects, resulting in …

Inflammation and clinical decline after adjuvant chemotherapy in older adults with breast cancer: results from the Hurria Older Patients Prospective Study

J Ji, CL Sun, HJ Cohen, T Synold, H Muss… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Older breast cancer survivors are at increased risk of clinical decline after
adjuvant chemotherapy. This study aimed to evaluate whether inflammatory markers …

Management of older adults with colorectal cancer: the role of geriatric assessment

AA Ozluk, D Outlaw, M Akce, ME Fowler… - Clinical Colorectal …, 2023 - Elsevier
Older adults share a growing burden of cancer morbidity and mortality. This is present
across the spectrum of oncologic diagnoses and is particularly true with colorectal cancer …

Integrating geriatric assessment measures into National Cancer Institute clinical trials

A Magnuson, N Van der Walde, JM McKoy… - JNCI …, 2022 - academic.oup.com
To improve the care of older adults with cancer, the traditional approach to clinical trial
design needs to be reconsidered. Older adults are underrepresented in clinical trials with …

Toxicity risk score and clinical decline after adjuvant chemotherapy in older breast cancer survivors

J Ji, CL Sun, HJ Cohen, HB Muss… - JNCI: Journal of the …, 2023 - academic.oup.com
Background Chemotoxicity risk scores were developed to predict grade 3-5 chemotherapy
toxicity in older women with early breast cancer. However, whether these toxicity risk scores …

Aging precisely: Precision medicine through the lens of an older adult

CA Austin, B Seligman, S Shan‐Bala… - Journal of the …, 2024 - Wiley Online Library
Precision medicine presents an opportunity to use novel, data‐driven strategies to improve
patient care. The field of precision medicine has undergone many advancements over the …