Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment.
Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible …

Preclinical models of human disease provide powerful tools for therapeutic discovery but
have limitations. This problem is especially apparent in the field of acute kidney injury (AKI) …

Background Acute kidney injury (AKI) remains associated with high morbidity and mortality,
despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage …

Simple Summary Increased stress is often observed in patients with kidney diseases,
contributing to renal injury progression. Flavonoids are naturally occurring plant compounds …

Extracorporeal life support (ECLS) encompasses a wide range of extracorporeal modalities
that offer short-and intermediate-term mechanical support to the failing heart or lung. Apart …

Acute kidney injury (AKI) is a common complication in hospitalized patients, associated
with> 50% mortality in those in intensive care who require renal replacement therapy. Data …

Interleukin 6 (IL-6) is pleiotropic cytokine with pathological pro-inflammatory effects in
various acute, chronic and infectious diseases. It is involved in a variety of biological …

Two metrics, a rise in serum creatinine concentration and a decrease in urine output, are
considered tantamount to the injury of the kidney tubule and the epithelial cells thereof (AKI) …

Exosomes are 40–100 nm membrane vesicles secreted into the extracellular space by
numerous cell types. These structures can be isolated from body fluids including urine and …

Acute kidney injury (AKI) is a common complication of pediatric cardiac surgery and is
associated with increased morbidity and mortality. Literature of AKI after pediatric cardiac …