The mammary gland is a compound, branched tubuloalveolar structure and a major
characteristic of mammals. The mammary gland has evolved from epidermal apocrine …

Ciliopathies are inherited human disorders caused by both motile and non‐motile cilia
dysfunction that form an important and rapidly expanding disease category. Ciliopathies are …

The primary cilium has recently stepped into the spotlight, as a flood of data show that this
organelle has crucial roles in vertebrate development and human genetic diseases. Cilia …

Neural stem and progenitor cells have a central role in the development and evolution of the
mammalian neocortex. In this review, we first provide a set of criteria to classify the various …

Cilia play many essential roles in fluid transport and cellular locomotion, and as sensory
hubs for a variety of signal transduction pathways. Despite having a conserved basic …

The primary cilium is an antenna-like organelle assembled on most types of quiescent and
differentiated mammalian cells. This immotile structure is essential for interpreting …

Fibroblast growth factor (FGF) signalling has been implicated during several phases of early
embryogenesis, including the patterning of the embryonic axes, the induction and/or …

Primary cilia protrude from most vertebrate cell bodies and act as specialized 'signalling
antennae'that can substantially lengthen or retract in minutes to hours in response to specific …

Although universally recognized as the source of cerebrospinal fluid (CSF), the choroid
plexus (ChP) has been one of the most understudied tissues in neuroscience. The reasons …

TGF-β family ligands function in inducing and patterning many tissues of the early vertebrate
embryonic body plan. Nodal signaling is essential for the specification of mesendodermal …