Nondestructive 3D pathology with light-sheet fluorescence microscopy for translational research and clinical assays

JTC Liu, AK Glaser, C Poudel… - Annual Review of …, 2023 - annualreviews.org
In recent years, there has been a revived appreciation for the importance of spatial context
and morphological phenotypes for both understanding disease progression and guiding …

Fluorescence lifetime of injected indocyanine green as a universal marker of solid tumours in patients

R Pal, TM Lwin, M Krishnamoorthy… - Nature Biomedical …, 2023 - nature.com
The surgical resection of solid tumours can be enhanced by fluorescence-guided imaging.
However, variable tumour uptake and incomplete clearance of fluorescent dyes reduces the …

Optical imaging technologies for in vivo cancer detection in low-resource settings

H Hou, R Mitbander, Y Tang, A Azimuddin… - Current opinion in …, 2023 - Elsevier
Cancer continues to affect underserved populations disproportionately. Novel optical
imaging technologies, which can provide rapid, non-invasive, and accurate cancer detection …

Scattering-based light-sheet microscopy imaging of human papillomavirus–associated squamous lesions of the anal canal: a proof-of-principle study

B Liang, J Zhao, Y Kim, KQ Barry-Holson, DB Bingham… - Modern Pathology, 2024 - Elsevier
Demand for anal cancer screening is expected to rise following the recent publication of the
Anal Cancer–HSIL Outcomes Research trial, which showed that treatment of high-grade …

Engineering the future of 3D pathology

JTC Liu, SSL Chow, R Colling… - The Journal of …, 2024 - Wiley Online Library
In recent years, technological advances in tissue preparation, high‐throughput volumetric
microscopy, and computational infrastructure have enabled rapid developments in …

Open-top Bessel beam two-photon light sheet microscopy for three-dimensional pathology

WY Park, J Yun, J Shin, BH Oh, G Yoon, SM Hong… - Elife, 2024 - elifesciences.org
Nondestructive pathology based on three-dimensional (3D) optical microscopy holds
promise as a complement to traditional destructive hematoxylin and eosin (H&E) stained …

Microcamera visualisation system to overcome specular reflections for tissue imaging

L Niemitz, SD van der Stel, S Sorensen, W Messina… - Micromachines, 2023 - mdpi.com
In vivo tissue imaging is an essential tool for medical diagnosis, surgical guidance, and
treatment. However, specular reflections caused by glossy tissue surfaces can significantly …

Role of in vivo imaging in Head and Neck cancer management

SB Mali - Oral Oncology, 2023 - Elsevier
Intravital microscopy (IVM) and optical coherency tomography (OCT) are powerful optical
imaging tools that allow visualization of dynamic biological activities in living subjects with …

[PDF][PDF] Oral leukoplakia: diagnosis and management revisited

I van der Waal - J Dent Indones, 2023 - pdfs.semanticscholar.org
The definition of oral leukoplakia has not much changed during the past five decades and is
still a definition by exclusion of 'known'lesions. Therefore, a diagnosis of leukoplakia is not …

Label-free imaging and histo-optical evaluation of head and neck cancers with multiphoton autofluorescence microscopy

PP Villarreal, R Pal, S Qiu, O Coblens… - Cancers, 2023 - mdpi.com
Simple Summary Efforts to identify lesions of head and neck cancers with high malignant
potential are important to improve patient outcomes, as 5-year survival rates remain low due …