Bone morphogenetic proteins: A powerful osteoinductive compound with non‐negligible side effects and limitations

A Oryan, S Alidadi, A Moshiri, A Bigham‐Sadegh - Biofactors, 2014 - Wiley Online Library
Healing and regeneration of large bone defects leading to non‐unions is a great concern in
orthopedic surgery. Since auto‐and allografts have limitations, bone tissue engineering and …

Bone substitutes and expanders in spine surgery: a review of their fusion efficacies

A Kadam, PW Millhouse, CK Kepler… - International Journal of …, 2016 - ijssurgery.com
Study Design A narrative review of literature. Objective This manuscript intends to provide a
review of clinically relevant bone substitutes and bone expanders for spinal surgery in terms …

Mimicking growth factors: role of small molecule scaffold additives in promoting tissue regeneration and repair

N Goonoo, A Bhaw-Luximon - RSC advances, 2019 - pubs.rsc.org
The primary aim of tissue engineering scaffolds is to mimic the in vivo environment and
promote tissue growth. In this quest, a number of strategies have been developed such as …

Unilateral pedicle screw fixation of lumber spine: A safe internal fixation method

S Yang, H **a, M Cong, A Guo, K Ma, M Song - Heliyon, 2022 - cell.com
Background Unilateral pedicle screw fixation several advantages, including reduced trauma
and low cost. However, its stability and safety have not been widely recognized. In this study …

Changes in spinal alignment following extreme lateral interbody fusion alone in patients with adult spinal deformity using computed tomography

A Hiyama, H Katoh, D Sakai, M Sato, M Tanaka… - Scientific Reports, 2019 - nature.com
This study examined the ability of the extreme lateral interbody fusion (XLIF) procedure to
restore coronal and sagittal alignments for patients with adult spinal deformity (ASD) using …

Transforaminal lumbar interbody fusion with rhBMP-2 in spinal deformity, spondylolisthesis, and degenerative disease—part 2: BMP dosage–related complications …

DG Crandall, J Revella, J Patterson, E Huish, M Chang… - Spine, 2013 - journals.lww.com
Study Design. Retrospective review of prospectively collected data. Objective. Without
industry funding, the study evaluated short-and long-term complications related to off-label …

Increased incidence of pseudarthrosis after unilateral instrumented transforaminal lumbar interbody fusion in patients with lumbar spondylosis

Y Gologorsky, B Skovrlj, J Steinberger… - … of Neurosurgery: Spine, 2014 - thejns.org
Object Transforaminal lumbar interbody fusion (TLIF) with segmental pedicular
instrumentation is a wellestablished procedure used to treat lumbar spondylosis with or …

Minimally invasive transforaminal lumbar interbody fusion (TLIF) for spondylolisthesis in 282 patients: in situ arthrodesis versus reduction

JK Scheer, B Auffinger, RH Wong, SK Lam… - World neurosurgery, 2015 - Elsevier
Objective The benefits of spondylolisthesis reduction via minimally invasive transforaminal
lumbar interbody fusion (MI-TLIF) remain poorly understood. The purpose was to compare …

The minimally effective dose of bone morphogenetic protein in posterior lumbar interbody fusion: a systematic review and meta-analysis

EJ Lytle, MH Lawless, G Paik, D Tong, TM Soo - The spine journal, 2020 - Elsevier
BACKGROUND CONTENT The risks and benefits of recombinant human bone
morphogenetic protein-2 (BMP) in posterior lumbar interbody fusion (PLIF) and …

Comparing minimally invasive and open transforaminal lumbar interbody fusion for treatment of degenerative lumbar disease: a meta-analysis

Z Sun, W Li, Z Yu, G Qiu - Chinese medical journal, 2013 - journals.lww.com
Background Transforaminal lumbar interbody fusion (TLIF) through a minimally invasive
approach (mTLIF) was introduced to reduce soft tissue injury and speed recovery. Studies …