Trends in develo** one-pot CRISPR diagnostics strategies
L Chen, M Hu, X Zhou - Trends in Biotechnology, 2024 - cell.com
The integration of nucleic acid amplification (NAA) with the CRISPR detection system has
led to significant advancements and opportunities for development in molecular diagnostics …
led to significant advancements and opportunities for development in molecular diagnostics …
CRISPR for companion diagnostics in low-resource settings
Q Xu, Q Xu, C Lyon, TY Hu - Lab on a Chip, 2024 - pubs.rsc.org
New point-of-care tests (POCTs), which are especially useful in low-resource settings, are
needed to expand screening capacity for diseases that cause significant mortality …
needed to expand screening capacity for diseases that cause significant mortality …
New design strategies for ultra-specific CRISPR-Cas13a-based RNA detection with single-nucleotide mismatch sensitivity
An increasingly pressing need for clinical diagnostics has required the development of novel
nucleic acid-based detection technologies that are sensitive, fast, and inexpensive, and that …
nucleic acid-based detection technologies that are sensitive, fast, and inexpensive, and that …
Recent advances in CRISPR-based biosensors for point-of-care pathogen detection
Infectious pathogens are pressing concerns due to their heavy toll on global health and
socioeconomic infrastructure. Rapid, sensitive, and specific pathogen detection methods are …
socioeconomic infrastructure. Rapid, sensitive, and specific pathogen detection methods are …
Agarose hydrogel-boosted one-tube RPA-CRISPR/Cas12a assay for robust point-of-care detection of zoonotic nematode Anisakis
L Zhao, H Wang, X Chen, L Wang… - Journal of Agricultural …, 2024 - ACS Publications
Rapid and accurate detection of the zoonotic nematode Anisakis is poised to control its
epidemic. The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas …
epidemic. The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas …
Advancements in CRISPR-Diagnostic Techniques for Rapid on-site Monitoring of Environmental Virus
Z Deng, W Liao, L Bu, J Li, J Li, L Wang, A Yuan… - TrAC Trends in …, 2024 - Elsevier
Highly sensitive and rapid environmental surveillance is crucial due to the significant role of
various environmental media in transmitting multiple viruses. Specifically, when examining …
various environmental media in transmitting multiple viruses. Specifically, when examining …
New design strategies for ultra-specific CRISPR-Cas13a-based RNA-diagnostic tools with single-nucleotide mismatch sensitivity
The pressing need for clinical diagnostics has required the development of novel nucleic
acid-based detection technologies that are sensitive, fast, and inexpensive, and that can be …
acid-based detection technologies that are sensitive, fast, and inexpensive, and that can be …
High-Throughput and Integrated CRISPR/Cas12a-Based Molecular Diagnosis Using a Deep Learning Enabled Microfluidic System
CRISPR/Cas-based molecular diagnosis demonstrates potent potential for sensitive and
rapid pathogen detection, notably in SARS-CoV-2 diagnosis and mutation tracking. Yet, a …
rapid pathogen detection, notably in SARS-CoV-2 diagnosis and mutation tracking. Yet, a …
Multiplexed Detection Strategies for Biosensors Based on the CRISPR-Cas System
C Wei, X Lei, S Yu - ACS Synthetic Biology, 2024 - ACS Publications
A growing number of applications require simultaneous detection of multiplexed nucleic acid
targets in a single reaction, which enables higher information density in combination with …
targets in a single reaction, which enables higher information density in combination with …
RPA-CRISPR/Cas12a assay for the diagnosis of bovine Anaplasma marginale infection
A Sutipatanasomboon, J Wongsantichon, S Sakdee… - Scientific Reports, 2024 - nature.com
Anaplasma marginale infection is one of the most common tick-borne diseases, causing a
substantial loss in the beef and dairy production industries. Once infected, the pathogen …
substantial loss in the beef and dairy production industries. Once infected, the pathogen …