The NF-κB transcription factor is the master regulator of the inflammatory response and is
essential for the homeostasis of the immune system. NF-κB regulates the transcription of …

Nuclear factor-κB (NF-κB) is a transcription factor that has crucial roles in inflammation,
immunity, cell proliferation and apoptosis. Activation of NF-κB mainly occurs via IκB kinase …

The pathophysiology of sepsis and septic shock involves complex cytokine and
inflammatory mediator networks. NF-κB activation is a central event leading to the activation …

The diverse cellular and biological functions of the nuclear factor kappa B (NF-κB) pathway,
together with the catastrophic consequences of its aberrant regulation, demand specific and …

The serine/threonine kinase Akt (cellular homolog of murine thymoma virus akt8 oncogene),
also known as PKB (protein kinase B), is activated by lipid products of phosphatidylinositol 3 …

The pleiotropic consequences of nuclear factor of kappa light polypeptide gene enhancer in
B‐cells (NF‐κB) pathway activation result from the combinatorial effects of the five subunits …

Intracranial aneurysms are common but are generally untreated, and their rupture can lead
to subarachnoid hemorrhage. Because of the poor prognosis associated with subarachnoid …

The NF-κB family of dimeric transcription factors regulates transcription by selectively
binding to DNA response elements present within promoters or enhancers of target genes …

LRRK2, a Parkinson's disease associated gene, is highly expressed in microglia in addition
to neurons; however, its function in microglia has not been evaluated. Using Lrrk2 …

With the reemergence of poultry diseases such as necrotic enteritis following the restriction
of in-feed antibiotics, the search for antibiotic alternatives has become critically important …