The anti-inflammatory properties of phytochemicals and their effects on epigenetic mechanisms involved in TLR4/NF-κB-mediated inflammation

HA Saleh, MH Yousef, A Abdelnaser - Frontiers in immunology, 2021 - frontiersin.org
Innate immune response induces positive inflammatory transducers and regulators in order
to attack pathogens, while simultaneously negative signaling regulators are transcribed to …

The role of phytochemicals in sepsis: A mechanistic and therapeutic perspective

B Alikiaii, M Bagherniya, G Askari, TP Johnston… - …, 2021 - Wiley Online Library
Sepsis and septic shock are still a leading cause of mortality and morbidity in intensive care
units worldwide. Sepsis is an uncontrolled and excessive response of the innate immune …

MiR-143-3p functions as a tumor suppressor by regulating cell proliferation, invasion and epithelial–mesenchymal transition by targeting QKI-5 in esophageal …

Z He, J Yi, X Liu, J Chen, S Han, L **, L Chen, H Song - Molecular cancer, 2016 - Springer
Abstract Background Dysregulation of microRNAs (miRNAs) have been demonstrated to
contribute to carcinogenesis. MiR-143-3p has been identified to function as a tumor …

Cross-talk between macrophages and atrial myocytes in atrial fibrillation

Z Sun, D Zhou, X **e, S Wang, Z Wang, W Zhao… - Basic research in …, 2016 - Springer
Increased macrophage accumulation occurs in the atria of patients with atrial fibrillation (AF).
However, the phenotype and functions of the macrophages in AF remain unclear. We …

NF-kB-regulated exosomal miR-155 promotes the inflammation associated with arsenite carcinogenesis

C Chen, F Luo, X Liu, L Lu, H Xu, Q Yang, J Xue, L Shi… - Cancer letters, 2017 - Elsevier
In the cancer microenvironment, extracellular communication allows various types of cells to
coordinate and execute biological functions. Emerging evidence indicates that exosomes …

QKI, a miR‐200 target gene, suppresses epithelial‐to‐mesenchymal transition and tumor growth

EJ Kim, JS Kim, S Lee, H Lee, JS Yoon… - … journal of cancer, 2019 - Wiley Online Library
The microRNA‐200 (miR‐200) family plays a major role in specifying epithelial phenotype
by preventing expression of the transcription repressors ZEB1 and ZEB2, which are well …

[HTML][HTML] Divergent processing of cell stress signals as the basis of cancer progression: Licensing NFκB on Chromatin

SA Vlahopoulos - International Journal of Molecular Sciences, 2024 - mdpi.com
Inflammation is activated by diverse triggers that induce the expression of cytokines and
adhesion molecules, which permit a succession of molecules and cells to deliver stimuli and …

The role of immune cells in atrial fibrillation

Y Liu, Q Shi, Y Ma, Q Liu - Journal of Molecular and Cellular Cardiology, 2018 - Elsevier
Atrial fibrillation (AF) is the most common sustained arrhythmia, but its mechanisms are
poorly understood. Recently, accumulating evidence indicates a link between immune …

Anti-inflammatory effects of curcumin are associated with down regulating microRNA-155 in LPS-treated macrophages and mice

F Ma, F Liu, L Ding, M You, H Yue, Y Zhou… - Pharmaceutical …, 2017 - Taylor & Francis
Context: The natural polyphenolic compound curcumin has been proved to modulate innate
immune responses and possess anti-inflammatory properties. Nevertheless, the mechanism …

Emerging functions of the Quaking RNA‐binding proteins and link to human diseases

L Darbelli, S Richard - Wiley Interdisciplinary Reviews: RNA, 2016 - Wiley Online Library
RNA‐binding proteins (RBPs) are essential players in RNA metabolism including key
cellular processes from pre‐mRNA splicing to mRNA translation. The K homology‐type …