Chagas disease in immunocompromised patients

EH Clark, LA Messenger, JD Whitman… - Clinical Microbiology …, 2024 - journals.asm.org
As Chagas disease remains prevalent in the Americas, it is important that healthcare
professionals and researchers are aware of the screening, diagnosis, monitoring, and …

Pathology and pathogenesis of Chagas heart disease

KM Bonney, DJ Luthringer, SA Kim… - Annual Review of …, 2019 - annualreviews.org
Chagas heart disease is an inflammatory cardiomyopathy that develops in approximately
one-third of people infected with the protozoan parasite Trypanosoma cruzi. One way T …

SBC guideline on the diagnosis and treatment of patients with cardiomyopathy of Chagas disease–2023

JA Marin-Neto, A Rassi Jr, GMM Oliveira… - Arquivos brasileiros de …, 2023 - SciELO Brasil
SciELO - Brasil - Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com
Cardiomiopatia da Doença de Chagas – 2023 Diretriz da SBC sobre Diagnóstico e …

Current understanding of immunity to Trypanosoma cruzi infection and pathogenesis of Chagas disease

FS Machado, WO Dutra, L Esper, KJ Gollob… - Seminars in …, 2012 - Springer
Chagas disease caused by Trypanosoma cruzi remains an important neglected tropical
disease and a cause of significant morbidity and mortality. No longer confined to endemic …

Immunoregulatory networks in human C hagas disease

WO Dutra, CAS Menezes, LMD Magalhães… - Parasite …, 2014 - Wiley Online Library
Chagas disease, caused by the infection with T rypanosoma cruzi, is endemic in all L atin A
merica. Due to the increase in population migration, C hagas disease has spread worldwide …

New insights into Trypanosoma cruzi genetic diversity, and its influence on parasite biology and clinical outcomes

MMA Silvestrini, GD Alessio, BED Frias… - Frontiers in …, 2024 - frontiersin.org
Chagas disease, caused by Trypanosoma cruzi, remains a serious public health problem
worldwide. The parasite was subdivided into six distinct genetic groups, called “discrete …

IL-10/STAT3/SOCS3 axis is involved in the anti-inflammatory effect of benznidazole

ÁC Cevey, FN Penas, CD Alba Soto, GA Mirkin… - Frontiers in …, 2019 - frontiersin.org
Anti-parasitic treatment for Chagas disease mainly relies on benznidazole, which is virtually
the only drug available in the market. Besides its anti-parasitic effects, benznidazole has anti …

Vesicles from different Trypanosoma cruzi strains trigger differential innate and chronic immune responses

PM Nogueira, K Ribeiro, ACO Silveira… - Journal of …, 2015 - Taylor & Francis
Trypomastigote forms of Trypanosoma cruzi, the causative agent of Chagas Disease, shed
extracellular vesicles (EVs) enriched with glycoproteins of the gp85/trans-sialidase (TS) …

Diretriz da SBC sobre Diagnóstico e Tratamento de Pacientes com Cardiomiopatia da Doença de Chagas–2023

JA Marin-Neto, A Rassi Jr, GMM Oliveira… - Arquivos Brasileiros …, 2023 - SciELO Brasil
A DC (tripanossomíase americana) é entidade mórbida transmissível, potencialmente fatal,
causada pelo protozoário parasita T. cruzi e que integra o grupo de doenças tropicais …