Choroid plexus Aquaporins in CSF homeostasis and the Glymphatic system: their relevance for Alzheimer's disease
The glymphatic system, a fluid-clearance pathway involved in brain waste clearance, is
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …
known to be impaired in neurological disorders, including Alzheimer's disease (AD). For this …
The glymphatic system's role in traumatic brain injury-related neurodegeneration
In at least some individuals who suffer a traumatic brain injury (TBI), there exists a risk of
future neurodegenerative illness. This review focuses on the association between the brain …
future neurodegenerative illness. This review focuses on the association between the brain …
Association between choroid plexus volume and cognition in Parkinson disease
SH Jeong, HJ Jeong, MK Sunwoo… - European Journal of …, 2023 - Wiley Online Library
Background and purpose The choroid plexus (CP) clears harmful metabolites from the
central nervous system as part of the glymphatic system. We investigated the association of …
central nervous system as part of the glymphatic system. We investigated the association of …
Choroid plexus volume as a novel candidate neuroimaging marker of the Alzheimer's continuum
J Jiang, Z Zhuo, A Wang, W Li, S Jiang, Y Duan… - Alzheimer's Research & …, 2024 - Springer
Abstract Background Enlarged choroid plexus (ChP) volume has been reported in patients
with Alzheimer's disease (AD) and inversely correlated with cognitive performance …
with Alzheimer's disease (AD) and inversely correlated with cognitive performance …
[HTML][HTML] Mechanisms of cerebrospinal fluid and brain interstitial fluid production
J **ang, Y Hua, G **, RF Keep - Neurobiology of disease, 2023 - Elsevier
Fluid homeostasis is fundamental for brain function with cerebral edema and hydrocephalus
both being major neurological conditions. Fluid movement from blood into brain is one …
both being major neurological conditions. Fluid movement from blood into brain is one …
Anti‐seizure medication response and the glymphatic system in patients with focal epilepsy
Background and purpose We aimed to evaluate (i) glymphatic system function in patients
with focal epilepsy in comparison with healthy controls, and (ii) the association between anti …
with focal epilepsy in comparison with healthy controls, and (ii) the association between anti …
Multi-omics Mendelian randomization integrating GWAS, eQTL and pQTL data revealed GSTM4 as a potential drug target for migraine
X Sun, B Chen, Y Qi, M Wei, W Chen, X Wu… - The Journal of …, 2024 - Springer
Introduction Migraine, as a complex neurological disease, brings heavy burden to patients
and society. Despite the availability of established therapies, existing medications have …
and society. Despite the availability of established therapies, existing medications have …
Cerebrospinal fluid turnover as a driver of brain clearance
Cerebrospinal fluid (CSF) has historically been considered to function as a sink for brain‐
derived waste disposal. Recent work suggested that CSF interacts even more intensely with …
derived waste disposal. Recent work suggested that CSF interacts even more intensely with …
Hypertension: causes and consequences of circadian rhythms in blood pressure
Hypertension is extremely common, affecting approximately 1 in every 2 adults globally.
Chronic hypertension is the leading modifiable risk factor for cardiovascular disease and …
Chronic hypertension is the leading modifiable risk factor for cardiovascular disease and …
Circadian mechanisms in brain fluid biology
VS Vizcarra, RM Fame, LM Hablitz - Circulation Research, 2024 - Am Heart Assoc
The brain is a complex organ, fundamentally changing across the day to perform basic
functions like sleep, thought, and regulating whole-body physiology. This requires a …
functions like sleep, thought, and regulating whole-body physiology. This requires a …