Frailty is an emerging global health burden, with major implications for clinical practice and
public health. The prevalence of frailty is expected to rise alongside rapid growth in the …

Persistent low-grade inflammation and premature ageing are hallmarks of the uremic
phenotype and contribute to impaired health status, reduced quality of life, and premature …

Background Patients with kidney failure undergoing hemodialysis experience physical
deconditioning and multimorbidity. Exercise interventions may mitigate this outcome, but …

Hemodialysis is the most common type of treatment for end-stage renal disease (ESRD).
Frailty is associated with poor outcomes such as higher mortality. ESRD patients have a …

Frailty, the state of increased vulnerability to physical stressors as a result of progressive and
sustained degeneration in multiple physiological systems, is common in those with chronic …

The prevalence of older adults undergoing surgery is expected to increase as the population
ages. 1 Because of physiologic decline and loss of functional reserve, older patients are at a …

The construct of frailty was first developed in gerontology to help identify older adults with
increased vulnerability when confronted with a health stressor. This article is a review of …

SARS‐CoV‐2 infection has emerged as not only a pulmonary but also potentially multi‐
organ disease, which may cause long‐term structural damage of different organ systems …

Patients with non-dialysis chronic kidney disease (CKD) are at greater risk of early mortality
and decreased physical function with an advance in the stage of CKD. However, the effect of …

Frailty is a multidimensional clinical syndrome characterised by low physical activity,
reduced strength, accumulation of multi‐organ deficits, decreased physiological reserve and …