Intranasal delivery of poly (d-glucosamine) encrusted self-assembled lipidic nanovesicles to enhanced brain uptake of thymoquinone for management of Glioblastoma …
S Trivedi, S Kause, V Belgamwar - Journal of Drug Delivery Science and …, 2023 - Elsevier
Glioblastoma Multiforme (GBM) is a grade IV primary malignant brain tumour, which is highly
infiltrative and exhibits a poor prognosis which results in high mortality. Low solubility and …
infiltrative and exhibits a poor prognosis which results in high mortality. Low solubility and …
[HTML][HTML] Biomimetic curcumin-loaded liposomes for the treatment of dry eyes and meibomian gland dysfunction: an in vivo study
V Baranauskas, R Jaruseviciene… - Journal of Clinical …, 2024 - mdpi.com
Background/Objectives: Meibomian gland dysfunction (MGD) and dry eye syndrome (DES)
are common eye diseases characterized by altered tear film stability and inflammation of the …
are common eye diseases characterized by altered tear film stability and inflammation of the …
Bioequivalence Requirements for Orally Inhaled and Nasal Drug Products and Use of Novel Physiologically Based Biopharmaceutics Modeling Approaches for …
A Rachapally, R Boddu, S Kollipara… - Journal of Pharmaceutical …, 2024 - Elsevier
Orally inhaled and nasal drug products (OINDPs) are complex due to the interplay between
the device, formulation, and patient characteristics. Establishing bioequivalence (BE) of …
the device, formulation, and patient characteristics. Establishing bioequivalence (BE) of …
QbD assisted development and validation of UV spectroscopic method in estimation of silymarin
Background: Silymarin is a flavonoid utilised in liver dysfunction for years; new studies have
emphasised its potential utility as a therapy for nanoparticulate targeting in many other …
emphasised its potential utility as a therapy for nanoparticulate targeting in many other …
The Influence of Shape Parameters on Unidirectional Drug Release from 3D Printed Implants and Prediction of Release from Implants with Individualized Shapes
V Domsta, C Hänsch, S Lenz, Z Gao, F Matin-Mann… - Pharmaceutics, 2023 - mdpi.com
The local treatment of diseases by drug-eluting implants is a promising tool to enable
successful therapy under potentially reduced systemic side effects. Especially, the highly …
successful therapy under potentially reduced systemic side effects. Especially, the highly …
Pharmacokinetics and pharmacodynamics of curcumin-loaded solid lipid nanoparticles in the management of streptozotocin-induced diabetes mellitus: application of …
Due to poor bioavailability and chemical instability, the effectiveness of curcumin is
negligible in the treatment of numerous diseases. Solid lipid nanoparticles (SLNs) increase …
negligible in the treatment of numerous diseases. Solid lipid nanoparticles (SLNs) increase …
[PDF][PDF] Design and Characterization of pH Dependent Phase Transition System of Almotriptan Malate for Nasal Drug Delivery System by Employing Factorial Design
V Malviya, S Pande - Ind. J. Pharm. Edu. Res, 2024 - ijper.org
Introduction: Nasal medication delivery uses nasal mucosa for faster and higher drug
absorption. Transmucosal nasal administration is promising. Many medicines obtain …
absorption. Transmucosal nasal administration is promising. Many medicines obtain …
A bioanalytical assay for estimation of thymoquinone in rats cerebrospinal fluid and brain tissues of nasally administrated thymoquinone loaded lipo-polymeric …
S Trivedi, R Agade, V Belgamwar - Journal of Pharmacological and …, 2024 - Elsevier
Thymoquinone (TH) has been one of the major phytochemical used in the treatment of
cancers since long time, especially in the management of glioblastoma multiforme (GBM) …
cancers since long time, especially in the management of glioblastoma multiforme (GBM) …
Analytical profiling, method development and validation for estimation of Chrysin in nasal simulated fluid using HPLC method with applicability in-situ gelling system
B Kokate, V Belgamwar, S Bodhankar… - Journal of Liquid …, 2025 - Taylor & Francis
Chrysin (CHY) belongs to the flavone group and has multiple activities, such as antioxidant,
anti-inflammatory, anti-apoptotic, anti-cancer, and neuroprotection. Considering the various …
anti-inflammatory, anti-apoptotic, anti-cancer, and neuroprotection. Considering the various …
Optimization and fabrication of curcumin loaded solid lipid nanoparticles using box-Behnken design for nasal delivery
S Sharma, JB Sharma, S Bhatt… - … & Nanotechnology-Asia, 2022 - ingentaconnect.com
Aims: To prepare curcumin loaded solid lipid nanoparticles for nasal administration using
Box-Behnken design. Background: The effectiveness of curcumin in neurological disorders …
Box-Behnken design. Background: The effectiveness of curcumin in neurological disorders …