Snakebite envenoming

JM Gutiérrez, JJ Calvete, AG Habib… - Nature reviews Disease …, 2017 - nature.com
Snakebite envenoming is a neglected tropical disease that kills> 100,000 people and
maims> 400,000 people every year. Impoverished populations living in the rural tropics are …

Causes and consequences of snake venom variation

NR Casewell, TNW Jackson, AH Laustsen… - Trends in …, 2020 - cell.com
Snake venoms are mixtures of toxins that vary extensively between and within snake
species. This variability has serious consequences for the management of the world's 1.8 …

[PDF][PDF] Antivenomics and its role in enhancing cobra envenomation treatments: A review of current practices and future prospects

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

[HTML][HTML] Progressive loss of function in a limb enhancer during snake evolution

EZ Kvon, OK Kamneva, US Melo, I Barozzi… - Cell, 2016 - cell.com
The evolution of body shape is thought to be tightly coupled to changes in regulatory
sequences, but specific molecular events associated with major morphological transitions in …

[PDF][PDF] Innovative approaches to neutralizing cobra venom: Advances in antivenomics and recombinant antivenoms

I Karunarathna, K De Alvis, P Gunasena… - 2024 - researchgate.net
The King Cobra (Ophiophagus hannah) holds cultural significance and is one of the most
medically important venomous snakes worldwide. Envenomation by King Cobras often …

A field guide to whole‐genome sequencing, assembly and annotation

R Ekblom, JBW Wolf - Evolutionary applications, 2014 - Wiley Online Library
Genome sequencing projects were long confined to biomedical model organisms and
required the concerted effort of large consortia. Rapid progress in high‐throughput …

Multifunctional toxins in snake venoms and therapeutic implications: from pain to hemorrhage and necrosis

CR Ferraz, A Arrahman, C **e, NR Casewell… - Frontiers in ecology …, 2019 - frontiersin.org
Animal venoms have evolved over millions of years for prey capture and defense from
predators and rivals. Snake venoms, in particular, have evolved a wide diversity of peptides …

Evolution and diversity of transposable elements in vertebrate genomes

CG Sotero-Caio, RN Platt, A Suh… - Genome biology and …, 2017 - academic.oup.com
Transposable elements (TEs) are selfish genetic elements that mobilize in genomes via
transposition or retrotransposition and often make up large fractions of vertebrate genomes …

The Genome 10K Project: a way forward

KP Koepfli, B Paten… - Annu. Rev. Anim …, 2015 - annualreviews.org
The Genome 10K Project was established in 2009 by a consortium of biologists and
genome scientists determined to facilitate the sequencing and analysis of the complete …

Haemotoxic snake venoms: their functional activity, impact on snakebite victims and pharmaceutical promise

J Slagboom, J Kool, RA Harrison… - British journal of …, 2017 - Wiley Online Library
Snake venoms are mixtures of numerous proteinacious components that exert diverse
functional activities on a variety of physiological targets. Because the toxic constituents …