Overcoming barriers by local drug delivery with liposomes

SG Antimisiaris, A Marazioti, M Kannavou… - Advanced drug delivery …, 2021 - Elsevier
Localized or topical administration of drugs may be considered as a potential approach for
overcoming the problems caused by the various biological barriers encountered in drug …

Nanotherapeutics for nose-to-brain drug delivery: an approach to bypass the blood brain barrier

D Lee, T Minko - Pharmaceutics, 2021 - mdpi.com
Treatment of neurodegenerative diseases or other central nervous system (CNS) disorders
has always been a significant challenge. The nature of the blood-brain barrier (BBB) limits …

Recent advances in intranasal liposomes for drug, gene, and vaccine delivery

VA Duong, TTL Nguyen, HJ Maeng - Pharmaceutics, 2023 - mdpi.com
Liposomes are safe, biocompatible, and biodegradable spherical nanosized vesicles
produced from cholesterol and phospholipids. Recently, liposomes have been widely …

Progress in nasal drug delivery systems

F Laffleur, B Bauer - International journal of pharmaceutics, 2021 - Elsevier
Most of the available drugs are usually administered orally (eg in tablets or capsules) or by
parenteral injection in the case of substances being destroyed in the gastric environment or …

[HTML][HTML] Novel nano-drug delivery system for brain tumor treatment

Z Qiu, Z Yu, T Xu, L Wang, N Meng, H **, B Xu - Cells, 2022 - mdpi.com
As the most dangerous tumors, brain tumors are usually treated with surgical removal,
radiation therapy, and chemotherapy. However, due to the aggressive growth of gliomas …

Unravelling the in vivo dynamics of liposomes: Insights into biodistribution and cellular membrane interactions

S Paramshetti, M Angolkar, S Talath, RAM Osmani… - Life Sciences, 2024 - Elsevier
Liposomes, as a colloidal drug delivery system dating back to the 1960s, remain a focal
point of extensive research and stand as a highly efficient drug delivery method. The …

Exploring the impact of physicochemical properties of liposomal formulations on their in vivo fate

B Sheikholeslami, NW Lam, K Dua, M Haghi - Life Sciences, 2022 - Elsevier
Liposomes, vesicles composed of a phospholipid bilayer, are considered a remarkably
advanced drug delivery system due to their unique properties, including their …

Nasal delivery to the brain: harnessing nanoparticles for effective drug transport

S Gandhi, DH Shastri, J Shah, AB Nair, S Jacob - Pharmaceutics, 2024 - mdpi.com
The nose-to-brain drug-delivery system has emerged as a promising strategy to overcome
the challenges associated with conventional drug administration for central nervous system …

[HTML][HTML] Nanomaterials for skin delivery of cosmeceuticals and pharmaceuticals

EB Souto, AR Fernandes, C Martins-Gomes… - Applied Sciences, 2020 - mdpi.com
Featured Application The loading of pharmaceuticals and cosmeceuticals into
nanomaterials is discussed as new formulations for potential treatment of age-related skin …

Recent biomedical approaches for chitosan based materials as drug delivery nanocarriers

AT Iacob, FG Lupascu, M Apotrosoaei, IM Vasincu… - Pharmaceutics, 2021 - mdpi.com
In recent decades, drug delivery systems (DDSs) based on nanotechnology have been
attracting substantial interest in the pharmaceutical field, especially those developed based …