Regional, circuit and network heterogeneity of brain abnormalities in psychiatric disorders

A Segal, L Parkes, K Aquino, SM Kia, T Wolfers… - Nature …, 2023‏ - nature.com
The substantial individual heterogeneity that characterizes people with mental illness is
often ignored by classical case–control research, which relies on group mean comparisons …

Data-driven biomarkers better associate with stroke motor outcomes than theory-based biomarkers

ER Olafson, C Sperber, KW Jamison… - Brain …, 2024‏ - academic.oup.com
Chronic motor impairments are a leading cause of disability after stroke. Previous studies
have associated motor outcomes with the degree of damage to predefined structures in the …

[HTML][HTML] Bayesian lesion-deficit inference with Bayes factor map**: Key advantages, limitations, and a toolbox

C Sperber, L Gallucci, S Smaczny, R Umarova - NeuroImage, 2023‏ - Elsevier
Statistical lesion-symptom map** is largely dominated by frequentist approaches with null
hypothesis significance testing. They are popular for map** functional brain anatomy but …

Thalamocortical disconnection involved in pusher syndrome

H Rosenzopf, J Klingbeil, M Wawrzyniak, L Röhrig… - Brain, 2023‏ - academic.oup.com
The presence of both isolated thalamic and isolated cortical lesions have been reported in
the context of pusher syndrome—a disorder characterized by a disturbed perception of one's …

Map** sentence comprehension and syntactic complexity: evidence from 131 stroke survivors

N Biondo, MV Ivanova, AL Pracar, J Baldo… - Brain …, 2024‏ - academic.oup.com
Understanding and interpreting how words are organized in a sentence to convey distinct
meanings is a cornerstone of human communication. The neural underpinnings of this …

Longitudinal prediction of motor dysfunction after stroke: a disconnectome study

L Dulyan, L Talozzi, V Pacella, M Corbetta… - Brain Structure and …, 2022‏ - Springer
Motricity is the most commonly affected ability after a stroke. While many clinical studies
attempt to predict motor symptoms at different chronic time points after a stroke, longitudinal …

The contribution of cutaneous thermal signals to bodily self-awareness

G Salvato, PM Jenkinson, M Sellitto, D Crivelli… - Nature …, 2025‏ - nature.com
Thermosensory signals may contribute to the sense of body ownership, but their role
remains highly debated. We test this assumption within the framework of pathological body …

Frontoparietal structural network disconnections correlate with outcome after a severe stroke

L Frontzkowski, F Fehring, BM Frey… - Human Brain …, 2024‏ - Wiley Online Library
Structural disconnectome analyses have provided valuable insights into how a stroke lesion
results in widespread network disturbances and how these relate to deficits, recovery …

Mental flexibility depends on a largely distributed white matter network: Causal evidence from connectome-based lesion-symptom map**

M Anziano, M Mouthon, H Thoeny, C Sperber… - cortex, 2023‏ - Elsevier
Mental flexibility (MF) refers to the capacity to dynamically switch from one task to another.
Current neurocognitive models suggest that since this function requires interactions …

Incremental value of stroke-induced structural disconnection in predicting global cognitive impairment after stroke

C Pan, G Chen, P **g, G Li, Y Li, J Miao, W Sun… - Stroke, 2023‏ - ahajournals.org
Background: Poststroke cognitive impairment (PSCI) is highly prevalent in stroke survivors
and correlated with unfavorable clinical outcomes. This study aimed to identify the neural …