The pharmacokinetics and the pharmacodynamics of cannabinoids

CJ Lucas, P Galettis, J Schneider - British journal of clinical …, 2018 - Wiley Online Library
There is increasing interest in the use of cannabinoids for disease and symptom
management, but limited information available regarding their pharmacokinetics and …

Potential adverse drug events and drug–drug interactions with medical and consumer cannabidiol (CBD) use

JD Brown, AG Winterstein - Journal of clinical medicine, 2019 - mdpi.com
Cannabidiol (CBD) is ubiquitous in state-based medical cannabis programs and consumer
products for complementary health or recreational use. CBD has intrinsic pharmacologic …

Towards better delivery of cannabidiol (CBD)

SA Millar, RF Maguire, AS Yates, SE O'Sullivan - Pharmaceuticals, 2020 - mdpi.com
Cannabidiol (CBD) has substantial therapeutic potential, but its development as an effective
drug by the pharmaceutical industry is hindered by intrinsic characteristics such as low …

Cannabis and its secondary metabolites: their use as therapeutic drugs, toxicological aspects, and analytical determination

J Gonçalves, T Rosado, S Soares, AY Simão… - Medicines, 2019 - mdpi.com
Although the medicinal properties of Cannabis species have been known for centuries, the
interest on its main active secondary metabolites as therapeutic alternatives for several …

Cannabis sativa: Much more beyond Δ9-tetrahydrocannabinol

P Alves, C Amaral, N Teixeira… - Pharmacological …, 2020 - Elsevier
Cannabis is the most used illicit drug worldwide and its medicinal use is under discussion,
being regulated in several countries. However, the psychotropic effects of Δ 9 …

Cannabidiol—From plant to human body: A promising bioactive molecule with multi-target effects in cancer

B Kis, FC Ifrim, V Buda, S Avram, IZ Pavel… - International journal of …, 2019 - mdpi.com
Cannabis sativa L. is a plant long used for its textile fibers, seed oil, and oleoresin with
medicinal and psychoactive properties. It is the main source of phytocannabinoids, with over …

The potential for pharmacokinetic interactions between cannabis products and conventional medications

Y Qian, BJ Gurley, JS Markowitz - Journal of clinical …, 2019 - journals.lww.com
Purpose Increased cannabis use and recent drug approvals pose new challenges for
avoiding drug interactions between cannabis products and conventional medications. This …

Cannabidiol in the treatment of epilepsy: Current evidence and perspectives for further research

V Franco, M Bialer, E Perucca - Neuropharmacology, 2021 - Elsevier
The therapeutic potential of cannabidiol (CBD) in seizure disorders has been known for
many years, but it is only in the last decade that major progress has been made in …

Cannabinoids in medicine: a multifaceted exploration of types, therapeutic applications, and emerging opportunities in neurodegenerative diseases and cancer …

V Voicu, FM Brehar, C Toader, RA Covache-Busuioc… - Biomolecules, 2023 - mdpi.com
In this review article, we embark on a thorough exploration of cannabinoids, compounds that
have garnered considerable attention for their potential therapeutic applications. Initially, this …

An individuality of response to cannabinoids: challenges in safety and efficacy of cannabis products

S Kitdumrongthum, D Trachootham - Molecules, 2023 - mdpi.com
Since legalization, cannabis/marijuana has been gaining considerable attention as a
functional ingredient in food.∆-9 tetrahydrocannabinol (THC), cannabidiol (CBD), and other …