Neonatal sepsis
Neonatal sepsis is the cause of substantial morbidity and mortality. Precise estimates of
neonatal sepsis burden vary by setting. Differing estimates of disease burden have been …
neonatal sepsis burden vary by setting. Differing estimates of disease burden have been …
The effects of antibiotics on the microbiome throughout development and alternative approaches for therapeutic modulation
The widespread use of antibiotics in the past 80 years has saved millions of human lives,
facilitated technological progress and killed incalculable numbers of microbes, both …
facilitated technological progress and killed incalculable numbers of microbes, both …
Effects of early-life antibiotics on the develo** infant gut microbiome and resistome: a randomized trial
M Reyman, MA Van Houten, RL Watson… - Nature …, 2022 - nature.com
Broad-spectrum antibiotics for suspected early-onset neonatal sepsis (sEONS) may have
pronounced effects on gut microbiome development and selection of antimicrobial …
pronounced effects on gut microbiome development and selection of antimicrobial …
Development of the gut microbiota in infancy and its impact on health in later life
M Tanaka, J Nakayama - Allergology International, 2017 - jstage.jst.go.jp
abstract Gut microbial ecology and function are dynamic in infancy, but are stabilized in
childhood. The 'new friends' have a great impact on the development of the digestive tract …
childhood. The 'new friends' have a great impact on the development of the digestive tract …
The intestinal microbiome in early life: health and disease
Human microbial colonization begins at birth and continues to develop and modulate in
species abundance for about 3 years, until the microbiota becomes adult-like. During the …
species abundance for about 3 years, until the microbiota becomes adult-like. During the …
Antibiotics as deep modulators of gut microbiota: between good and evil
The recent increase in our knowledge of human gut microbiota has changed our view on
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …
antibiotics. Antibiotics are, indeed, no longer considered only beneficial, but also potentially …
Bench to bedside—new insights into the pathogenesis of necrotizing enterocolitis
Necrotizing enterocolitis (NEC) is the leading cause of death and disability from
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …
gastrointestinal disease in premature infants. Recent discoveries have shed light on a …
Gut microbiome and type 2 diabetes: where we are and where to go?
Type 2 diabetes mellitus (T2D) is a highly prevalent metabolic disorder characterized by an
imbalance in blood glucose level, altered lipid profile and high blood pressure. Genetic …
imbalance in blood glucose level, altered lipid profile and high blood pressure. Genetic …
Neonatal antibiotic exposure impairs child growth during the first six years of life by perturbing intestinal microbial colonization
A Uzan-Yulzari, O Turta, A Belogolovski, O Ziv… - Nature …, 2021 - nature.com
Exposure to antibiotics in the first days of life is thought to affect various physiological
aspects of neonatal development. Here, we investigate the long-term impact of antibiotic …
aspects of neonatal development. Here, we investigate the long-term impact of antibiotic …
Persistent metagenomic signatures of early-life hospitalization and antibiotic treatment in the infant gut microbiota and resistome
Hospitalized preterm infants receive frequent and often prolonged exposures to antibiotics
because they are vulnerable to infection. It is not known whether the short-term effects of …
because they are vulnerable to infection. It is not known whether the short-term effects of …