Adiponectin, a therapeutic target for obesity, diabetes, and endothelial dysfunction

AE Achari, SK Jain - International journal of molecular sciences, 2017 - mdpi.com
Adiponectin is the most abundant peptide secreted by adipocytes, whose reduction plays a
central role in obesity-related diseases, including insulin resistance/type 2 diabetes and …

Diabetes during pregnancy: a maternal disease complicating the course of pregnancy with long-term deleterious effects on the offspring. a clinical review

A Ornoy, M Becker, L Weinstein-Fudim… - International Journal of …, 2021 - mdpi.com
In spite of the huge progress in the treatment of diabetes mellitus, we are still in the situation
that both pregestational (PGDM) and gestational diabetes (GDM) impose an additional risk …

Adiponectin: role in physiology and pathophysiology

TMD Nguyen - International journal of preventive medicine, 2020 - journals.lww.com
Adiponectin, an adipokine secreted by adipocytes, is a well-known homeostatic factor for
regulating glucose levels, lipid metabolism, and insulin sensitivity through its anti …

The endocrine function of human placenta: an overview

MA Costa - Reproductive biomedicine online, 2016 - Elsevier
During pregnancy, several tightly coordinated and regulated processes take place to enable
proper fetal development and gestational success. The formation and development of the …

A vicious circle between insulin resistance and inflammation in nonalcoholic fatty liver disease

Z Chen, R Yu, Y **ong, F Du, S Zhu - Lipids in health and disease, 2017 - Springer
Nonalcoholic fatty liver disease (NAFLD) comprises a spectrum of diseases, including
simple steatosis, nonalcoholic steatohepatitis (NASH), liver cirrhosis and hepatocellular …

The complex interaction between obesity, metabolic syndrome and reproductive axis: a narrative review

K Michalakis, G Mintziori, A Kaprara, BC Tarlatzis… - Metabolism, 2013 - Elsevier
The aim of this narrative review is to provide current evidence for the interaction between
obesity, metabolic syndrome (MS) and reproductive axis. Gonadotropin-releasing hormone …

[PDF][PDF] The human placenta in gestational diabetes mellitus: the insulin and cytokine network

G Desoye, S Hauguel-de Mouzon - Diabetes care, 2007 - mundialsiglo21.com
The placenta is a complex fetal organ that fulfills pleiotropic roles during fetal growth. It
separates the maternal and fetal circulation, with which it is in contact through different …

Antidiabetic Potency, Antioxidant Effects, and Mode of Actions of Citrus reticulata Fruit Peel Hydroethanolic Extract, Hesperidin, and Quercetin in Nicotinamide …

AM Ali, MA Gabbar, SM Abdel-Twab… - Oxidative medicine …, 2020 - Wiley Online Library
This study is aimed at assessing the antihyperglycemic, antihyperlipidemic, and antioxidant
effects of Citrus reticulata (C. reticulata) fruit peel hydroethanolic extract and two flavonoids …

Adiponectin receptor signalling in the brain

J Thundyil, D Pavlovski, CG Sobey… - British journal of …, 2012 - Wiley Online Library
Adiponectin is an important adipocyte‐derived hormone that regulates metabolism of lipids
and glucose, and its receptors (AdipoR1, AdipoR2, T‐cadherin) appear to exert actions in …

APPL1: role in adiponectin signaling and beyond

SS Deepa, LQ Dong - American Journal of Physiology …, 2009 - journals.physiology.org
Adiponectin, an adipokine secreted by the white adipose tissue, plays an important role in
regulating glucose and lipid metabolism and controlling energy homeostasis in insulin …